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Upstream product

• 62689-67-2 α-Methylthio-2-thienylessigsaeuremethylester 
• 35320-27-5 2,2,2-trichloro-1-(thien-2-yl)-ethanol 
• 60639-74-9 1-methanesulfinyl-1-methylsulfanyl-2-thiophen-2-yl-ethene 

Relevant academic research and scientific papers

Process for preparing thiophene derivatives and thiophene derivatives obtained thereby

Process for the preparation of a series of thiophene derivatives, from which 2-thiopheneacetic acid derivatives can easily be prepared, in high yields and selectivity by using substituted or unsubstituted thiophenes as the starting materials by easy operations. 2-Thiopheneacetic acid derivatives are very useful compounds as the chemical modifier of penicillin and cephalosporin. Novel compounds, i.e. α-arylthio-2-thiopheneacetic acids are also disclosed. These compounds are useful as the intermediates of the synthesis of 2-thiopheneacetic acids.

Aromatic acetic acid derivatives having sulfur atom at alpha-position and process for their preparation

Aromatic acetic acid derivatives having a sulfur atom at the alpha-position, and a process for their preparation. Useful drugs can be produced from these derivatives.

Cephalosporins having a sulfur containing functional group in the 7-position side chain

Cephalosporins having a sulfur-containing functional group of the formula STR1 present at the carbon atom directly bonded to the thienyl or furyl group in the side chain of the 7-position of cephem derivatives. These compounds are useful as anti-bacterial agents against Gram-positive and Gram-negative bacteria.