(NLE8,18,TYR34)-PTH (1-34) AMIDE (BOVINE) is a synthetic form of the naturally occurring parathyroid hormone (PTH) found in cattle. This peptide hormone, consisting of 34 amino acids, is vital for regulating calcium and phosphate levels in the body. It primarily acts on bones and kidneys, stimulating the release of calcium from bones and enhancing its absorption in the kidneys, while also promoting the excretion of phosphate. This hormone is crucial for maintaining bone health and mineral balance in the body. Its synthetic version can be utilized for research purposes or as a medication for conditions such as osteoporosis and hypoparathyroidism.
64763-77-5
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Basic information
- Product Name: (NLE8,18,TYR34)-PTH (1-34) AMIDE (BOVINE)
- Synonyms: [NLE8,18, TYR34]-PARATHYROID HORMONE (1-34) AMIDE (BOVINE);(NLE8,18,TYR34)-PTH (1-34) AMIDE (BOVINE);PARATHYROID HORMONE [NLE8,18, TYR34]-BOVINE FRAGMENT 1-34 AMIDE;H-ALA-VAL-SER-GLU-ILE-GLN-PHE-NLE-HIS-ASN-LEU-GLY-LYS-HIS-LEU-SER-SER-NLE-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-TYR-NH2;nle8-18-tyr34-parathyroid hormone amide fragment;NLE8-18-TYR34-PARATHYROID HORMONE AMIDE FRAGMENT 1-;[nle8,18, tyr34]-pth fragment 1-34 amide bovine;ala-val-ser-glu-ile-gln-phe-nle-his-asn-leu-gly-lys-his-leu-ser-ser-nle-glu-arg-val-glu-trp-leu-arg-lys-lys-leu-gln-asp-val-his-asn-tyr-nh2
- CAS NO:64763-77-5
- Molecular Formula: C185H293N55O50
- Molecular Weight: 4087.64
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: (NLE8,18,TYR34)-PTH (1-34) AMIDE (BOVINE)(CAS DataBase Reference)
- NIST Chemistry Reference: (NLE8,18,TYR34)-PTH (1-34) AMIDE (BOVINE)(64763-77-5)
- EPA Substance Registry System: (NLE8,18,TYR34)-PTH (1-34) AMIDE (BOVINE)(64763-77-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 64763-77-5(Hazardous Substances Data)
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64763-77-5 Usage
Uses
Used in Pharmaceutical Industry:(NLE8,18,TYR34)-PTH (1-34) AMIDE (BOVINE) is used as a therapeutic agent for treating conditions like osteoporosis and hypoparathyroidism. It helps in increasing bone density and improving bone strength by stimulating the release of calcium from bones and enhancing its absorption in the kidneys.
Used in Research Applications:
(NLE8,18,TYR34)-PTH (1-34) AMIDE (BOVINE) is used as a research tool for studying the effects of parathyroid hormone on bone metabolism, calcium and phosphate regulation, and the underlying mechanisms of bone health and diseases. This synthetic form allows researchers to investigate the hormone's role in various physiological and pathological processes, contributing to a better understanding of bone biology and the development of novel therapeutic strategies for bone-related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 64763-77-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,7,6 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.Calculate Digit Verification of CAS Registry Number 64763-77:
(7*6)+(6*4)+(5*7)+(4*6)+(3*3)+(2*7)+(1*7)=155
155 % 10 = 5
So 64763-77-5 is a valid CAS Registry Number.
64763-77-5Upstream product
64763-77-5Downstream Products
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(NLE8,18,TYR34)-PTH (1-34) AMIDE (BOVINE)
