647828-37-3Relevant academic research and scientific papers
Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives: High-affinity ligands to the α2δ subunit of voltage gated calcium channels
Stearns, Brian A.,Anker, Naomi,Arruda, Jeannie M.,Campbell, Brian T.,Chen, Chixu,Cramer, Merryl,Hu, Tao,Jiang, Xiaohui,Park, Kenneth,Ren, Kun Kun,Sablad, Marciano,Santini, Angelina,Schaffhauser, Herve,Urban, Mark O.,Munoz, Benito
, p. 1295 - 1298 (2007/10/03)
A novel class of 6-aryl-6H-pyrrolo[3,4-d]pyridazine ligands for the α2δ subunit of voltage-gated calcium channels has been described. Substitutions in the aryl ring of the molecule were generally not tolerated, and resulted in diminished bindin
