647853-30-3

Basic information

• Product Name: Benzenesulfonamide, 3-bromo-N-[3-methyl-7-[(2-methylpropyl)amino]-1H-indazol-5-yl]-
• Synonyms: 3-Bromo-N-(7-isobutylamino-3-methyl-1H-indazol-5-yl)-benzenesulfonamide
• CAS NO: 647853-30-3
• Molecular Formula: C18H21BrN4O2S
• Molecular Weight: 437.35400
• Mol File: 647853-30-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 3-bromo-N-[3-methyl-7-[(2-methylpropyl)amino]-1H-indazol-5-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 3-bromo-N-[3-methyl-7-[(2-methylpropyl)amino]-1H-indazol-5-yl]-(647853-30-3)
• EPA Substance Registry System: Benzenesulfonamide, 3-bromo-N-[3-methyl-7-[(2-methylpropyl)amino]-1H-indazol-5-yl]-(647853-30-3)

Safety Data

• Hazardous Substances Data: 647853-30-3(Hazardous Substances Data)

Upstream product

• 1026031-05-9 isobutyl-(3-methyl-5-nitro-1H-indazol-7-yl)-amine 
• 647853-25-6 3-methyl-5-nitro-1H-indazol-7-ylamine 
• 23082-50-0 2'-chloro-5'-nitroacetophenone 
• 40621-84-9 3-methyl-5-nitro-1H-indazole 
• 2905-24-0 3-Bromobenzenesulfonyl chloride 

Relevant articles and documents

Structure-Based Design, Synthesis, and Antimicrobial Activity of Indazole-Derived SAH/MTA Nucleosidase Inhibitors

The structure-based design, synthesis, and biological activity of a novel indazole-containing inhibitor series for S-adenosyl homocysteine/methylthioadenosine (SAH/MTA) nucleosidase are described. Use of 5-aminoindazole as the core scaffold provided a structure-guided series of low nanomolar inhibitors with broad-spectrum antimicrobial activity. The implementation of structure-based methodologies provided a 6000-fold increase in potency over a short timeline (several months) and an economy of synthesized compounds.