647853-32-5 Usage
Uses
Used in Organic Synthesis:
3-(2-Hydroxyethyl)benzeneboronic acid is used as a reagent in organic synthesis for its ability to form stable and reversible complexes with diols, facilitating various chemical reactions and the synthesis of complex organic molecules.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 3-(2-Hydroxyethyl)benzeneboronic acid is used as a key intermediate in the synthesis of drugs, leveraging its reactivity and complex-forming properties to create new medicinal compounds.
Used in Agrochemicals:
3-(2-Hydroxyethyl)benzeneboronic acid is utilized as a component in the development of agrochemicals, where its chemical properties can be harnessed to create effective pesticides or other agricultural products.
Used in Materials Science:
In the field of materials science, 3-(2-Hydroxyethyl)benzeneboronic acid is used as a building block for the creation of new materials with specific properties, such as those with enhanced sensitivity or reactivity.
Used in Diabetes Treatment Research:
3-(2-Hydroxyethyl)benzeneboronic acid is being studied for its potential application in the treatment of diabetes, possibly due to its ability to interact with biological molecules relevant to glucose metabolism and insulin signaling.
Used in Cancer Treatment Research:
3-(2-Hydroxyethyl)benzeneboronic acid is also under investigation for its potential role in cancer treatment, where it might be employed to target specific biochemical pathways or cellular mechanisms in cancer cells.
Used in Molecular Sensors and Detection:
3-(2-Hydroxyethyl)benzeneboronic acid is used in the development of molecular sensors and detection systems, capitalizing on its complex-forming ability to create sensitive and selective analytical tools for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 647853-32-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,7,8,5 and 3 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 647853-32:
(8*6)+(7*4)+(6*7)+(5*8)+(4*5)+(3*3)+(2*3)+(1*2)=195
195 % 10 = 5
So 647853-32-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H11BO3/c10-5-4-7-2-1-3-8(6-7)9(11)12/h1-3,6,10-12H,4-5H2
647853-32-5Relevant academic research and scientific papers
Design and synthesis of novel meta-linked phenylglycine macrocyclic FVIIa inhibitors
Richter, Jeremy M.,Cheney, Daniel L.,Bates, J. Alex,Wei, Anzhi,Luettgen, Joseph M.,Rendina, Alan R.,Harper, Timothy M.,Narayanan, Rangaraj,Wong, Pancras C.,Seiffert, Dietmar,Wexler, Ruth R.,Priestley, E. Scott
supporting information, p. 67 - 72 (2017/12/12)
Two novel series of meta-linked phenylglycine-based macrocyclic FVIIa inhibitors have been designed to improve the rodent metabolic stability and PK observed with the precursor para-linked phenylglycine macrocycles. Through iterative structure-based design and optimization, the TF/ FVIIa Ki was improved to subnanomolar levels with good clotting activity, metabolic stability, and permeability.
MACROCYCLIC FACTOR VIIA INHIBITORS
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Paragraph 00127, (2015/01/09)
The present invention provides compounds of Formula (I) as defined in the specification and compositions comprising any of such novel compounds. These compounds are Factor VIIa inhibitors which may be used as medicaments.
