647854-53-3

Upstream product

• 3943-74-6 4-hydroxy-3-methoxybenzoic acid methyl ester 
• 171002-53-2 methyl 3-methoxy-4-(2-propenoxy)benzoate 

Downstream Products

• 199484-25-8 4-hydroxy-3-methoxy-5-propylbenzoic acid methyl ester 
• 85316-77-4 methyl 4-hydroxy-3-methoxy-5-(3-methylbut-2-enyl)benzoate 
• 1352196-27-0 methyl 4-(tert-butyldimethylsilyloxy)-3-methoxy-5-(3-methylbut-2-enyl)benzoate 
• 1352196-21-4 methyl 4-(triisopropylsilyloxy)-3-methoxy-5-(3-methylbut-2-enyl)benzoate 
• 1352196-15-6 methyl 4-(tert-butyldiphenylsilyloxy)-3-methoxy-5-(3-methylbut-2-enyl)benzoate 

Relevant academic research and scientific papers

ANTIVIRAL HETEROCYCLIC COMPOUNDS

The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

First enantioselective synthesis of methyl (+)-7-methoxyanodendroate, an antitubercular dihydrobenzofuran

An enantioselective synthesis of methyl (+)-7-methoxyanodendroate was achieved utilising a Claisen rearrangement, a Grubbs cross-metathesis, and a Shi epoxidation-cyclisation sequence, confirming the absolute configuration assigned to the natural product.

N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY

Novel N-hydroxyamide derivatives are disclosed. These N-hydroxyamide derivatives inhibit UPD-3O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase, an enzyme present in gram negative bacteria and are therefore useful as antimicrobials and antibiotics. Methods of synthesis and of use of the compounds are also disclosed.