64825-54-3Relevant academic research and scientific papers
ACETAL-BASED CLEAVABLE LINKERS
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Paragraph 0144-0145, (2020/12/29)
The current invention concerns compounds, such as antibody-conjugates, with an enhanced selectivity of payload release inside a tumour or in the tumour microenvironment versus payload release in circulation or in healthy cells. The enhanced selectivity is
REGIO- AND DIASTEREOSELECTIVITY OF ENOL ETHER FORMATION BY 1,4-SIGMATROPIC SHIFTS OF HYDROGEN IN CARBONYL YLIDES
Lottes, Andrew C.,Landgrebe, John A.,Larsen, Kristin
, p. 4089 - 4092 (2007/10/02)
Treatment of aliphatic ketones with ethyl diazoacetate in the presence of a catalyst results in the regio- and (where appropriate) diastereoselective formation of enol ethers which arise by an intramolecular 1,4-hydrogen shift from an intermediate carbony
