648415-79-6

Upstream product

• 648415-77-4 N-(4-chloro-2-trifluoromethylphenyl)thiourea 
• 155538-41-3 2-amino-6-chloro-4-trifluoromethyl-1,3-benzothiazole 

Downstream Products

• 648415-92-3 (7-chloro-3-methyl-5-trifluoromethyl-4H-benzo[1,4]thiazin-2-yl)-(4-chloro-phenyl)-methanone 
• 958300-85-1 4-chloro-2-(2-chloro-6-nitro-phenylsulfanyl)-6-trifluoromethyl-phenylamine 
• 958300-83-9 2-(4-bromo-2-nitro-phenylsulfanyl)-4-chloro-6-trifluoromethyl-phenylamine 
• 958300-84-0 4-chloro-2-(2-nitro-phenylsulfanyl)-6-trifluoromethyl-phenylamine 
• 958300-82-8 4-chloro-2-(4-chloro-2-nitro-phenylsulfanyl)-6-trifluoromethyl-phenylamine 
• 958300-88-4 N-[4-chloro-2-(2-nitro-phenylsulfanyl)-6-trifluoromethyl-phenyl]-formamide 
• 958300-86-2 N-[4-chloro-2-(4-chloro-2-nitro-phenylsulfanyl)-6-trifluoromethyl-phenyl]-formamide 
• 958300-89-5 N-[4-chloro-2-(2-chloro-6-nitro-phenylsulfanyl)-6-trifluoromethyl-phenyl]-formamide 
• 958300-87-3 N-[2-(4-bromo-2-nitro-phenylsulfanyl)-4-chloro-6-trifluoromethyl-phenyl]-formamide 
• 648415-91-2 (7-chloro-3-methyl-5-trifluoromethyl-4H-benzo[1,4]thiazin-2-yl)-m-tolyl-methanone 

Relevant academic research and scientific papers

Synthesis of bioactive substituted pyrazolylbenzothiazinones

Abstract Pyrazolylbenzothiazinones have been synthesized in good yields by the reaction of 2-hydrazinocarbonymethyl-3,4-dihydro-2H-1,4-benzothiazin-3-ones with β-diketone in the presence of ethanol. The structures of synthesized pyrazolylbenzothiazinones were confirmed on the basis of their analytical and spectral data. The antimicrobial activities of the synthesized compounds have also been included.

Synthesis of 7-chloro-5-trifluoromethyl/7-fluoro/7-trifluoromethyl-4H-1,4-benzothiazines as antimicrobial agents

7-Chloro-5-trifluoromethyl/7-fluoro/7-trifluoromethyl-4H-1,4-benzothiazines have been synthesized by 2-amino-5-fluoro/5-trifluoromethyl/5-chloro-3-trifluoromethyl benzenethiols condensed with β-diketone/β-ketoesters in the presence of DMSO involving oxidative cyclization. Pharmacological activities have also been included.

Synthesis of 2-amino-5-chloro-3-(trifluoromethyl)benzenethiol and conversion into 4H-1,4-benzothiazines and their sulfones

The synthesis of 2-amino-5-chloro-3-(trifluoromethyl)benzenethiol was achieved by hydrolytic cleavage of 2-amino-6-chloro-4- (trifluoromethyl)benzothiazole which was prepared by cyclization of 4-chloro-2-(trifluoromethyl)phenylthiourea by bromine in chlor