648438-79-3

Upstream product

• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 79669-49-1 5-bromo-2-methylbenzoic acid 
• 258886-04-3 (5-bromo-2-methylphenyl)methanol 
• 343322-82-7 ethyl [(4-mercapto-2-methylphenyl)oxy]acetate 

Downstream Products

• 638215-23-3 {[2-methyl-4-({[4-methyl-4'-(trifluoromethyl)-3-biphenylyl]methyl}thio)phenyl]oxy}acetic acid 

Relevant academic research and scientific papers

PHENYLALKANOIC ACID AND PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS

The present invention provides a compound of formula (I):wherein:R1 and R2 are independently H or C1-3 alkyl;X represents a O or (CH2)n where n is 0, 1 or 2;R3and R4 independently represent H, C1-3 alkyl, -OCH3, -CF3, allyl, or halogen;X1 represents O, S, SO2, SO, or CH2;R5 and R6 independently represent hydrogen, C1-6 alkyl (including branched alkyl and optionally substituted by one or more halogens or C1-6alkoxy), or together with the carbon atom to which they are bonded form a 3-6 membered cycloalkyl ring;R7 represents a phenyl or a 6 membered heteroaryl group containing 1, 2 or 3 nitrogen atoms wherein the phenyl or heteroaryl group is substituted by 1, 2 or 3 moieties selected from the group consisting of halogen, C1-6 alkoxy, C1-6 alkyl, CF3, hydroxy, or phenyl (which may be optionally substituted by one or more C1-3 alkyl, -OC1-3 alkyl, CN, acetyl, hydroxy, halogen or CF3).