648449-01-8

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 4-chloroquinoline-6-carboxylate is used as a potential pharmaceutical compound for its possible applications in drug development. Its unique structure, including the methyl group, chlorine atom, and carboxylate functional group, may contribute to its pharmacological properties, making it a candidate for further research and development in the pharmaceutical field.
Used in Chemical Industry:
Methyl 4-chloroquinoline-6-carboxylate is used as a chemical intermediate in the synthesis of various compounds. Its quinoline derivative nature allows it to be a valuable building block in the production of dyes, agrochemicals, and other specialty chemicals, contributing to the chemical industry's diverse product offerings.

Upstream product

• 38896-30-9 6-(methoxycarbonyl)quinoline 
• 358368-09-9 1-oxy-quinoline-6-carboxylic acid methyl ester 

Relevant academic research and scientific papers

THERAPEUTIC INHIBITORY COMPOUNDS

The invention provides compounds of Formula I and Formula II: A-B-C-D-E-F-G-J (I) C-D-E-F-G-J (II) wherein A, B, C, D, E, F, G, and J have any of the values defined in the specification, and salts thereof. The compounds are useful for inhibiting plasma kallikrein, and for treating a disease or condition in an animal where inhibition of plasma kallikrein is indicated.

FUSED 1,4-DIHYDRODIOXIN DERIVATIVES AS INHIBITORS OF HEAT SHOCK TRANSCRIPTION FACTOR 1

The present invention relates to compounds of formula I wherein A1, A2 R4 and Q are as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 (HSF1). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.

TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS

Compounds of Formula (I) are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. Compounds of Formula (I) have a structure where the definitions of the variables are provided herein.