64858-29-3

Basic information

• Product Name: Pyrimidine, 5-(2-pyridinyl)- (9CI)
• Synonyms: Pyrimidine, 5-(2-pyridinyl)- (9CI);5-(Pyridin-2-yl)pyrimidine
• CAS NO: 64858-29-3
• Molecular Formula: C₉H₇N₃
• Molecular Weight: 157.17198
• Product Categories: PYRIMIDINE;QUINAZOLINE
• Mol File: 64858-29-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 314.566°C at 760 mmHg
• Flash Point: 146.885°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.586
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Pyrimidine, 5-(2-pyridinyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrimidine, 5-(2-pyridinyl)- (9CI)(64858-29-3)
• EPA Substance Registry System: Pyrimidine, 5-(2-pyridinyl)- (9CI)(64858-29-3)

Safety Data

• Hazardous Substances Data: 64858-29-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H7N3/c1-2-4-12-9(3-1)8-5-10-7-11-6-8/h1-7H

Upstream product

• 289-95-2 PYRIMIDINE 
• 17624-36-1 2-pyridyllithium 
• 4595-59-9 5-bromopyrimidine 
• 21970-13-8 (pyridin-2-yl)magnesium bromide 
• 67-68-5 dimethyl sulfoxide 
• 6515-13-5 2-isopropenylpyridine 
• 1122-62-9 2-acetylpyridine 
• 110-86-1 pyridine 
• 109-04-6 2-bromo-pyridine 
• 109299-78-7 pyrimidine 5-boronic acid 
• 109-09-1 2-chloropyridine 
• 17997-47-6 2-tri-n-butylstannylpyridine 
• 65007-00-3 pyridin-2-yl trifluoromethanesulfonate 

Relevant articles and documents

Metallation of pyridin-2-yldiazines. Use of pyridine ring as ortho-directing group. Diazines. Part 45

Starting from commercial chlorodiazines, we report the synthesis of pyridin-2-yldiazines. The first lithiation and functionalization of these compounds are reported and the regioselectivity of the metallation is discussed. The functionalization via the metallation reaction, provides a new access to substituted pyridin-2-yldiazines, which could be used as building blocks in supramolecules.

A General, Multimetallic Cross-Ullmann Biheteroaryl Synthesis from Heteroaryl Halides and Heteroaryl Triflates

Despite their importance to medicine and materials science, the synthesis of biheteroaryls by cross-coupling remains challenging. We describe here a new, general approach to biheteroaryls: the Ni-and Pd-catalyzed multimetallic cross-Ullmann coupling of he

Remarkable catalytic activity of [PdCl2(CH3CN) 2] in Suzuki-Miyaura cross-coupling reaction in aqueous media under mild conditions

[PdCl2(CH3CN)2] (2 mol%) was found to be an efficient catalyst for the Suzuki-Miyaura cross coupling reaction between aryl bromide and aryl boronic acid in water solvent at 45 °C. The scope of the protocol was extended to various aryl bromides and aryl boronic acids. In general, an effective method has been developed for the Suzuki-Miyaura cross coupling reaction by using a phosphine-free Pd catalyst.