6487-91-8

Usage

Structure

2-(3-Methylphenyl)ethanethioamide is a thioamide derivative with a substituent of 3-methylphenyl on the ethanethioamide backbone.

Usage

It is used in organic synthesis and research, particularly in pharmaceutical applications.

Potential applications

It may have potential applications in drug development and has been studied for its potential therapeutic properties.

Chemical and biological properties

As a thioamide, it may exhibit interesting chemical and biological properties that warrant further investigation.

InChI:InChI=1/C9H11NS/c1-7-3-2-4-8(5-7)6-9(10)11/h2-5H,6H2,1H3,(H2,10,11)

Upstream product

• 2947-60-6 3-methylbenzyl cyanide 
• 90765-38-1 3-methylphenylacetamide 

Downstream Products

• 867314-48-5 5-methyl-2-(3-methylbenzyl)-1,3-thiazol-4-carboxylic acid ethyl ester 
• 1318758-26-7 tert-butyl [4-methyl-2-(3-methylbenzyl)-1,3-thiazol-5-yl]carbamate 
• 1225720-18-2 4-methyl-2-(3-methylbenzyl)-1,3-thiazole-5-carboxylic acid 
• 1318757-10-6 1-methyl-N-[4-methyl-2-(3-methylbenzyl)-1,3-thiazol-5-yl]-1H-pyrazole-5-carboxamide 
• 867314-46-3 4-methyl-2-(3-methyl-benzyl)-1,3-thiazole-5-carboxylic acid ethyl ester 
• 250258-71-0 2-{2-[2-(3-methyl-benzyl)-thiazol-4-yl]-ethyl}-isoindole-1,3-dione 

Relevant academic research and scientific papers

THIAZOLE DERIVATIVE

Provided is a compound having an agonist action on GPR52, which is useful as a prophylactic or therapeutic drug for mental diseases such as schizophrenia and the like, and the like. A compound represented by the formula (I): wherein each symbol is as defi

PHENYLTHIOACETIC ACID DERIVATIVES AND USE THEREOF

The invention relates to novel phenylthioacetic acid derivatives of formula (I), to a method for the production thereof, to the use thereof for the treatment and/or prophylaxis of diseases, in addition to the use thereof in the production of medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prevention of cardiovascular diseases, in particular dyslipidaemia and arteriosclerosis. The compounds act as modulators for the PRAR-alpha receptor.

Histamine H1 receptor ligands. Part I. Novel thiazol-4-ylethanamine derivatives: Synthesis and in vitro pharmacology

A series of 2-substituted thiazol-4-ylethanamines have been synthesized and tested for their histaminergic H1-receptor activities. The compounds with 2-phenyl substitution, regardless of the different physicochemical properties of the meta-substituents at the phenyl ring, showed weak H1-agonistic activity with pD2 values ranging from 4.35 to 5.36. When the phenyl group was replaced by a benzyl group, the resulting compounds all exhibited weak H1-antagonistic activity (pA2: 4.14-4.82). Copyright (C) 1999 Elsevier Science S.A.

Serotonin antagonists

A compound of the formula EQU1 or an acid addition salt thereof wherein R1 and R2 are the same or different and each is a phenyl or thien-2-yl group optionally substituted in one or more positions by a substituent selected from the class consisting of halogen, lower alkyl, lower alkoxy, hydroxy, lower alkylthio, phenyl, phenoxy, phenyl-(lower-alkyl) and phenyl-(lower-alkoxy), each of the said phenyl, phenoxy, phenyl-(lower-alkyl) and phenyl-(lower-alkoxy) substituent groups being optionally substituted in one or more positions by a member selected from the class consisting of halogen, lower alkyl, lower alkoxy, hydroxy, and lower alkylthio; A1 is a divalent straight or branched alkylene group containing from two to six carbon atoms and one or two divalent atoms which are each an oxygen or sulphur atom, provided that there are at least two carbon atoms between the divalent atom and the --NH-- group and between the two divalent atoms; and A2 is the methylene group --CH2 --.