6487-91-8

Basic information

• Product Name: 2-(3-METHYLPHENYL)ETHANETHIOAMIDE
• Synonyms: 2-(3-METHYLPHENYL)ETHANETHIOAMIDE;2-(3-Methylphenyl)thioacetaMide, 97%
• CAS NO: 6487-91-8
• Molecular Formula: C₉H₁₁NS
• Molecular Weight: 165.26
• Mol File: 6487-91-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 120-124℃
• Boiling Point: 294.1°C at 760 mmHg
• Flash Point: 131.7°C
• Appearance: /
• Density: 1.122g/cm³
• Vapor Pressure: 0.00166mmHg at 25°C
• Refractive Index: 1.616
• Sensitive: Air Sensitive
• CAS DataBase Reference: 2-(3-METHYLPHENYL)ETHANETHIOAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-METHYLPHENYL)ETHANETHIOAMIDE(6487-91-8)
• EPA Substance Registry System: 2-(3-METHYLPHENYL)ETHANETHIOAMIDE(6487-91-8)

Safety Data

• Hazardous Substances Data: 6487-91-8(Hazardous Substances Data)

Usage

Structure

2-(3-Methylphenyl)ethanethioamide is a thioamide derivative with a substituent of 3-methylphenyl on the ethanethioamide backbone.

Usage

It is used in organic synthesis and research, particularly in pharmaceutical applications.

Potential applications

It may have potential applications in drug development and has been studied for its potential therapeutic properties.

Chemical and biological properties

As a thioamide, it may exhibit interesting chemical and biological properties that warrant further investigation.

InChI:InChI=1/C9H11NS/c1-7-3-2-4-8(5-7)6-9(10)11/h2-5H,6H2,1H3,(H2,10,11)

Upstream product

• 2947-60-6 3-methylbenzyl cyanide 
• 90765-38-1 3-methylphenylacetamide 

Downstream Products

• 867314-48-5 5-methyl-2-(3-methylbenzyl)-1,3-thiazol-4-carboxylic acid ethyl ester 
• 1318758-26-7 tert-butyl [4-methyl-2-(3-methylbenzyl)-1,3-thiazol-5-yl]carbamate 
• 1225720-18-2 4-methyl-2-(3-methylbenzyl)-1,3-thiazole-5-carboxylic acid 
• 1318757-10-6 1-methyl-N-[4-methyl-2-(3-methylbenzyl)-1,3-thiazol-5-yl]-1H-pyrazole-5-carboxamide 
• 867314-46-3 4-methyl-2-(3-methyl-benzyl)-1,3-thiazole-5-carboxylic acid ethyl ester 
• 250258-71-0 2-{2-[2-(3-methyl-benzyl)-thiazol-4-yl]-ethyl}-isoindole-1,3-dione 

Relevant articles and documents

THIAZOLE DERIVATIVE

Provided is a compound having an agonist action on GPR52, which is useful as a prophylactic or therapeutic drug for mental diseases such as schizophrenia and the like, and the like. A compound represented by the formula (I): wherein each symbol is as defi

Histamine H1 receptor ligands. Part I. Novel thiazol-4-ylethanamine derivatives: Synthesis and in vitro pharmacology

A series of 2-substituted thiazol-4-ylethanamines have been synthesized and tested for their histaminergic H1-receptor activities. The compounds with 2-phenyl substitution, regardless of the different physicochemical properties of the meta-substituents at the phenyl ring, showed weak H1-agonistic activity with pD2 values ranging from 4.35 to 5.36. When the phenyl group was replaced by a benzyl group, the resulting compounds all exhibited weak H1-antagonistic activity (pA2: 4.14-4.82). Copyright (C) 1999 Elsevier Science S.A.