648895-46-9 Usage
Uses
Used in Pharmaceutical Research:
1-(4-FLUORO-BENZOYL)-PIPERIDIN-4-ONE is used as a building block for the synthesis of various pharmaceutical drugs and organic compounds. Its unique chemical properties and reactivity, particularly due to the presence of the fluorine atom, make it a valuable component in the development of new medications and therapeutic agents.
Used in Chemical Research:
In the field of chemical research, 1-(4-FLUORO-BENZOYL)-PIPERIDIN-4-ONE is used as a key intermediate in the synthesis of complex organic molecules. Its diverse biological activities and pharmacological properties make it a promising candidate for further exploration and development in the chemical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 648895-46-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,8,8,9 and 5 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 648895-46:
(8*6)+(7*4)+(6*8)+(5*8)+(4*9)+(3*5)+(2*4)+(1*6)=229
229 % 10 = 9
So 648895-46-9 is a valid CAS Registry Number.
648895-46-9Relevant academic research and scientific papers
Synthesis of heteroarylpiperazines and heteroarylbipiperidines with a restricted side chain and their affinities for 5-HT1A receptor
Yoo, Kyung Ho,Choi, Hyun Sik,Kim, Dong Chan,Shin, Kye Jung,Kim, Dong Jin,Song, Yun Seon,Jin, Changbae
, p. 208 - 215 (2007/10/03)
Heteroarylpiperazine and heteroarylbipiperidine derivatives, bearing a 4-piperidine ring instead of an alkylamino side chain to give the semi-rigidity, were prepared and evaluated for their abilities to displace [3H] 8-OH-DPAT binding to the rat hippocampal synaptic membranes. These compounds showed low to moderate affinities for 5-HT1A receptor, with Ki values ranging from 6912 nM to 232 nM. Of these compounds, 8 b and 15 e exhibited the best affinities for 5-HT1A receptor with Ki values of 232 nM and 338 nM, respectively.
