6489-61-8

Basic information

• Product Name: Metampicillin sodium
• Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-6-[2-(methyleneamino)-2-phenylacetamido]-7-oxo-, monosodiumsalt, D-(-)- (8CI); 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3,3-dimethyl-6-[[(2R)-(methyleneamino)phenylacetyl]amino]-7-oxo-, monosodiumsalt, (2S,5R,6R)- (9CI); 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3,3-dimethyl-6-[[(methyleneamino)phenylacetyl]amino]-7-oxo-, monosodium salt,[2S-[2a,5a,6b(S*)]]-; Bonopen; Lancilline; Metampicillin sodium; Methyleneampicillinsodium salt; Sodium metampicillin; Sodium methyleneampicillin; Suvipen
• CAS NO: 6489-61-8
• Molecular Formula: C17H18N3NaO4S
• Molecular Weight: 383.39729
• Mol File: 6489-61-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Metampicillin sodium(CAS DataBase Reference)
• NIST Chemistry Reference: Metampicillin sodium(6489-61-8)
• EPA Substance Registry System: Metampicillin sodium(6489-61-8)

Safety Data

• Hazardous Substances Data: 6489-61-8(Hazardous Substances Data)

Usage

Originator

Magnipen ,Clin-Comar-Byla ,Italy ,1969

Manufacturing Process

0.01 mol of 6-[D(-)α-(aminophenylacetamido)]-penicillanic acid was suspended in 150 cc of water cooled to +5°C and treated with 0.01 mol of sodium bicarbonate. The solution was treated with 0.01 mol of formaldehyde in aqueous solution, with agitation. The solution was then filtered to eliminate traces of insoluble product and the filtrate was lyophilized. Sodium 6-[D(-)-alpha-(methyleneamino-phenylacetamido)]-penicillanate was obtained.

Therapeutic Function

Antibacterial