Bavituximab is a monoclonal antibody that specifically targets and binds to phosphatidylserine (PS), a molecule typically found on the inner leaflet of cell membranes but exposed on the surface of tumor cells and virus-infected cells, creating an immunosuppressive environment. By binding to PS, bavituximab activates the immune system to recognize and destroy these abnormal cells. It has demonstrated potential in preclinical and clinical studies for the treatment of various cancers, viral infections, and other diseases. Furthermore, bavituximab has been investigated in combination with other cancer therapies, including chemotherapy, radiation, and immunotherapy, to enhance their efficacy and overcome resistance.
648904-28-3
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Basic information
- Product Name: Bavituximab
- Synonyms: BAVITUXIMAB;Tarvacin
- CAS NO:648904-28-3
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Bavituximab(CAS DataBase Reference)
- NIST Chemistry Reference: Bavituximab(648904-28-3)
- EPA Substance Registry System: Bavituximab(648904-28-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 648904-28-3(Hazardous Substances Data)
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648904-28-3 Usage
Uses
Used in Cancer Treatment:Bavituximab is used as a therapeutic agent for the treatment of various cancers. It targets the exposed phosphatidylserine on the surface of tumor cells, activating the immune system to recognize and destroy these abnormal cells. This mechanism of action has shown promise in preclinical and clinical studies, making bavituximab a valuable treatment option for a range of cancers.
Used in Viral Infections:
Bavituximab is also used as a therapeutic agent for the treatment of viral infections. By binding to the exposed phosphatidylserine on the surface of virus-infected cells, it helps the immune system to recognize and eliminate these infected cells, potentially reducing the severity and duration of viral infections.
Used in Combination Therapy:
Bavituximab is used in combination with other cancer therapies, such as chemotherapy, radiation, and immunotherapy, to enhance their efficacy and overcome resistance. The synergistic effect of bavituximab with these therapies has the potential to improve treatment outcomes and provide better options for patients with cancer.
Used in Immunotherapy:
Bavituximab is used as an immunotherapy agent, leveraging the body's immune system to target and destroy abnormal cells. By binding to the exposed phosphatidylserine on tumor cells and virus-infected cells, it activates the immune response, making it a promising option for immunotherapy in various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 648904-28-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,8,9,0 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.Calculate Digit Verification of CAS Registry Number 648904-28:
(8*6)+(7*4)+(6*8)+(5*9)+(4*0)+(3*4)+(2*2)+(1*8)=193
193 % 10 = 3
So 648904-28-3 is a valid CAS Registry Number.
648904-28-3Upstream product
648904-28-3Downstream Products
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Bavituximab
