648905-83-3Relevant academic research and scientific papers
A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats
Hummel, Conrad W.,Geiser, Andrew G.,Bryant, Henry U.,Cohen, Ilene R.,Dally, Robert D.,Fong, Kin Chiu,Frank, Scott A.,Hinklin, Ronald,Jones, Scott A.,Lewis, George,McCann, Denis J.,Rudmann, Daniel G.,Shepherd, Timothy A.,Tian, Hongqi,Wallace, Owen B.,Wang, Minmin,Wang, Yong,Dodge, Jeffrey A.
, p. 6772 - 6775 (2007/10/03)
The design of a novel selective estrogen receptor modulator (SERM) for the potential treatment of uterine leiomyoma is described. 16 (LY2066948-HCl) binds with high affinity to estrogen receptors α and β (ERα and ERβ, respectively) and is a potent uterine
SELECTIVE ESTROGEN RECEPTOR MODULATORS CONTAINING A PHENYLSULFONYL GROUP
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Page/Page column 70, (2008/06/13)
The present invention relates to a selective estrogen receptor modulator of formula I or a pharmaceutical acid addition salt thereof; useful, e.g., for treating endometriosis and/or uterine leiomyoma/leiomyomata.
