648909-47-1Relevant academic research and scientific papers
An efficient synthetic approach towards a single diastereomer of (2R,3R)-N 2,N 3-bis((S)-1-phenylethyl)butane-2,3-diamine via metalation and demetalation
Cho, Juhyun,Nayab, Saira,Jeong, Jong Hwa
, p. 9 - 17 (2019/09/03)
Abstract: A facile synthetic approach has been adopted towards the synthesis of (2R,3R)-N2,N3-bis((S)-1-phenylethyl)butane-2,3-diamine via demetalation of its dichloro Zn(II) complex, which itself was separated from a mixture of dias
Titanium(IV)(salen) and yanadium(V)(salen) complexes derived from C 2- and C1-symmetric diamines for asymmetric cyanohydrin synthesis
Belokon', Yuri N.,Hunt, Jamie,North, Michael
scheme or table, p. 2150 - 2154 (2009/05/07)
Titanium and vanadium salen complexes have been prepared from C 2- and C1-symmetric acyclic diamines. All of the complexes catalysed the asymmetric addition of trimethylsilyl cyanide to benzaldehyde and the sense of asymmetric induction was determined by the nature of the substituents. The vanadium complex of a valine-derived diamine gave good results with a range of aromatic and aliphatic aldehydes. Georg Thieme Verlag Stuttgart.
A new chiral masked form of glyoxal diimine
Martelli, Gianluca,Savoia, Diego
, p. 1531 - 1540 (2007/10/03)
(3R,4R,5R,6R)-3,6-Diphenyl-N,N′-bis[(S)-1-phenylethyl]octa-1, 7-diene-4,5-diamine, by treatment with organolithium reagents RLi in controlled experimental conditions, underwent rearrangement and/or substitution of one or two branched allyl(s) by the R group(s). Hence, this diene behaves as a masked form of the chiral glyoxal diimine from that it is prepared, allowing the preparation of C1-symmetric 1,2-disubstituted 1,2-diamines, which are generally not available by the direct addition of organometallic reagents to the diimine, and C2-symmetric 1,2-diamines with good diastereoselectivities.
