648919-28-2

Upstream product

• 172966-53-9 (S)-N-{3-[3-fluoro-4-(4-oxo-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide 
• 596136-34-4 N-[[(5S)-3-[3-fluoro-4-(4-cyanomethylidene-piperidinyl)-phenyl]-2-oxo-5-oxazolidinyl]-methyl]-acetamide 

Relevant academic research and scientific papers

Methylidene oxazolidinone compound and preparation method thereof

A methylidene oxazolidinone compound represented by formula (1) or a pharmaceutically acceptable salt thereof, and a preparation method thereof, showing superior antimicrobial activities against gram-positive germs including resistant strains such as meth

Synthesis and in vitro activity of new methylenepiperidinyl and methylenepyrrolidinyl oxazolidinone antibacterial agents

We have prepared and evaluated the antibacterial activities of a series of substituted methylenepiperidinyl and methylenepyrrolidinyl oxazolidinones against several gram-positive strains including the resistant strains of Staphyloccus and Enterococcus, such as MRSA, CRSA, MSSA and VRE. Some of them showed comparable or superior in vitro activities (MIC) to vancomycin.