648927-86-0Relevant academic research and scientific papers
METHOD FOR THE PREPARATION OF (3S,3S') 4,4'-DISULFANEDIYLBIS (3-AMINOBUTANE 1-SULFONIC ACID)
-
Page/Page column 3; 10; 11, (2012/04/23)
The present invention relates to a new method for the preparation of (3S,3S') 4,4'-disulfanediylbis(3-aminobutane 1-sulfonic acid) in five steps from (S)-ethyl 2-(benzyloxycarbonylamino)-4-(neopentyloxysulfonyl)butanoate A.
Method for the preparation of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid)
-
Page/Page column 8, (2012/04/23)
The present invention relates to a new method for the preparation of (3S,3S') 4,4'-disulfanediylbis(3-aminobutane 1-sulfonic acid) in five steps from (S)-ethyl 2-(benzyloxycarbonylamino)-4-(neopentyloxysulfonyl)butanoate A.
Synthesis and separation of tritiated inhibitors of aminopeptidase A and their prodrugs
Inguimbert, Nicolas,Coric, Pascale,Dhotel, Helene,Llorens-Cortes, Catherine,Fournie-Zaluski, Marie-Claude,Roques, Bernard P.
, p. 997 - 1005 (2007/10/03)
With the aim of studying the bioavailability of two related aminopeptidase A (APA) inhibitors, we have synthesized tritiated disulfide prodrugs. These molecules, 4,4′-dithiobis-(3,3′-amino)-1,1′-butanesulfonic acid (RB 150) and its 2,2-dimethylpropyl este
