648928-64-7Relevant academic research and scientific papers
Spiraling steroids: Organic crystals with asymmetric nanometer-scale channels
Sisson, Adam L.,Del Amo Sanchez, Vicente,Magro, Germinal,Griffin, Alex M. E.,Shah, Shilen,Charmant, Jonathan P.H.,Davis, Anthony P.
, p. 6878 - 6881 (2005)
(Figure Presented) Crystals with broad robust channels are rare, especially if self-assembled without the aid of metal ions. Three such crystals were prepared based on a common steroid motif. The channels formed are chiral, directional, aligned, and wide
A steroid-based receptor for unprotected amino acids: The enantioselective recognition of l-tryptophan
Sirikulkajorn, Anchalee,Tuntulani, Thawatchai,Ruangpornvisuti, Vithaya,Tomapatanaget, Boosayarat,Davis, Anthony P.
, p. 7423 - 7428 (2010)
A cholapod receptor possessing urea binding sites at C3, C7, and C12 positions and with an intrinsic chiral structure was synthesized, and the binding abilities toward amino acids in both l- and d- forms (Trp, Phe, Leu, and Ala) were studied using 1
Structure-activity relationships in cholapod anion carriers: Enhanced transmembrane chloride transport through substituent tuning
McNally, Beth A.,Koulov, Atanas V.,Lambert, Timothy N.,Smith, Bradley D.,Joos, Jean-Baptiste,Sisson, Adam L.,Clare, John P.,Sgarlata, Valentine,Judd, Luke W.,Magro, Germinal,Davis, Anthony P.
supporting information; scheme or table, p. 9599 - 9606 (2009/11/30)
Chloride transport by a series of steroid-based "cholapod" receptors/carriers was studied in vesicles. The principal method involved preincorporation of the cholapods in the vesicle membranes, and the use of lucigenin fluorescence quenching to detect inwa
Facilitated phosphatidylserine (PS) flip-flop and thrombin activation using a synthetic PS scramblase
Boon, J. Middleton,Lambert, Timothy N.,Sisson, Adam L.,Davis, Anthony P.,Smith, Bradley D.
, p. 8195 - 8201 (2007/10/03)
A cationic steroid with a hydrogen-bonding pocket that has an affinity for anionic phospholipid headgroups was synthesized and shown to strongly promote the translocation or flip-flop of a fluorescent, C6NBD-labeled phosphatidylserine probe (C
