648930-22-7Relevant academic research and scientific papers
Organocatalytic synthesis of N-phenylisoxazolidin-5-ones and a one-pot synthesis of β-amino acid esters
Seayad, Jayasree,Patra, Pranab Kumar,Zhang, Yugen,Ying, Jackie Y.
supporting information; experimental part, p. 953 - 956 (2009/04/10)
A novel N-heterocyclic carbene (NHC)-catalyzed C-N bond formation by the reaction of α,β-unsaturated aldehydes and nitrosobenzene to N-phenylisoxazolidin-5-ones, followed by an acid-catalyzed esterification and Bamberger-like rearrangement in a mild one-pot protocol leads to N-p-methoxyphenyl (N-PMP) protected β-amino acid esters.
Oxazolines as chiral building blocks for imidazolium salts and N-heterocyclic carbene ligands
Glorius, Frank,Altenhoff, Gereon,Goddard, Richard,Lehmann, Christian
, p. 2704 - 2705 (2007/10/03)
Enantiomerically pure imidazolium triflates can be readily prepared from bioxazolines and oxazolineimines; deprotonation of imidazolium triflate 2 gives a chiral N-heterocyclic carbene that can act as a ligand in a catalytically active palladium complex.
