64897-39-8

Upstream product

• 81701-18-0 4-Methoxy-2,2-dicarbethoxy-6,7-methylenedioxy-1-(3',4',5'-trimethoxyphenyl)tetralin 
• 64897-37-6 diethyl 8-oxo-5-(3,4,5-trimethoxyphenyl)-7,8-dihydronaphtho-[2,3-d][1,3]dioxole-6,6(5H)-dicarboxylate 
• 50-00-0 formaldehyd 
• 64897-38-7 1,2,3,4-tetrahydro-6,7-methylenedioxy-4-oxo-1-(3,4,5-trimethoxyphenyl)naphthalene-2-carboxylic acid 
• 75404-02-3 5-Benzo[1,3]dioxol-5-yl-5-hydroxy-2-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-3-carboxylic acid ethyl ester 

Downstream Products

• 64937-82-2 (5α,5aα,8aβ)-5,5a,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)furo<3',4':6,7>naphtho<2,3-d>-1,3-dioxole-6(5aH),9-(8aH)-dione 

Relevant academic research and scientific papers

Total Synthesis of ( +/-)-Picropodophillone

Following model studies, the synthesis of (+/-)-picropodophillone was completed by first cyclopropanating the appropriate chalcone (11) with ethoxycarbonyl dimethylsulphonium methylide.Treatment of the resulting cyclopropyl ketone with stannic chloride in

Total Synthesis of (+/-)-4'-Demethyl-4-epipodophyllotoxin by Insertion-Cyclization

The total synthesis of (+/-)-4'-O-demethyl-4-epipodophyllotoxin (3) is accomplished in 13 steps and 2.4percent overall yield from piperonal through the use of an "insertion-cyclization" reaction to form the aryltetralin ring system.