64900-65-8

Basic information

• Product Name: 2-CHLOROBENZENESULFONYL ISOCYANATE
• Synonyms: 2-CHLOROBENZENESULFONYL ISOCYANATE;2-CHLOROBENZENSULFONYL ISOCYANATE;2-Chlorophenylsulfonyl Isocyanate;2-Chlorobenzenesulfonyl;o-chloro benzene sulfonylisocyanate;2-Chlorobenzenesulfonl isocyanate;2-Chlorobenzenesulfonyl isocyanate 90%;2-chloro-N-(oxomethylidene)benzenesulfonamide
• CAS NO: 64900-65-8
• Molecular Formula: C₇H₄ClNO₃S
• Molecular Weight: 217.63
• Product Categories: Isocyanates;Nitrogen Compounds;Organic Building Blocks;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 64900-65-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 285 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.484 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00114mmHg at 25°C
• Refractive Index: n20/D 1.559(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-CHLOROBENZENESULFONYL ISOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLOROBENZENESULFONYL ISOCYANATE(64900-65-8)
• EPA Substance Registry System: 2-CHLOROBENZENESULFONYL ISOCYANATE(64900-65-8)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 3265 8/PG 1
• WGK Germany: 3
• Hazardous Substances Data: 64900-65-8(Hazardous Substances Data)

Usage

Uses

2-Chlorobenzenesulfonyl isocyanate may be used in the synthesis of N-thiazolyl-N′-(2-chlorobenzenesulfonyl)urea derivatives and N-(2-chlorophenylsulfonyl)-N′-(4-methoxy-6-methyl-triazin-2-yl)urea.

General Description

2-Chlorobenzenesulfonyl isocyanate is an aryl isocyanate that can be synthesized by the catalytic carbonylation of potassium N,2- dichlorobenzenesulfonamidate in acetonitrile. The C-acylation of nitrogen bearing heterocycles using 2-chlorobenzenesulfonyl isocyanate has been reported.

InChI:InChI=1/C7H4ClNO3S/c8-6-3-1-2-4-7(6)13(11,12)9-5-10/h1-4H

Upstream product

• 6961-82-6 2-chlorobenzenesulfonamide 
• 111-36-4 n-butyl isocyanide 
• 79-37-8 oxalyl dichloride 
• 75-44-5 phosgene 
• 201230-82-2 carbon monoxide 
• 125069-33-2 Kalium N-chlor-2-chlorbenzolsulfonamidat 

Downstream Products

• 1270930-62-5 C₂₈H₂₈ClN₃O₄S₂ 
• 64902-72-3 1-(2-chlorophenylsulfonyl)-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea 
• 64900-66-9 chlorsulfuron 
• 68983-89-1 1-(2-chloro-benzenesulfonyl)-3-(5,6-dimethyl-[1,2,4]triazin-3-yl)-urea 
• 64902-63-2 chlorsulfuron 
• 130019-59-9 1-Chloro-2-[[[4-chloro-6-(2,4-dichloro-1-phenoxy)pyrimidin-2-yl]-aminocarbonyl]aminosulfonyl]benzene 

Relevant articles and documents

Production process for improving quality of sulfonyl isocyanate

The invention discloses a production process for improving the quality of sulfonyl isocyanate. The production process comprises the steps of mixing a sulfanilamide raw material and xylene according toa certain ratio to form a sulfanilamide solution, adding a certain amount of xylene into a synthesis kettle, heating, controlling the temperature at 110 to 115 DEG C, adding the sulfanilamide solution into the synthesis kettle through a transfer pump at a certain rate; dropwise adding a catalyst and introducing gaseous phosgene at the same time, paying attention to that the catalyst must be dropwise added 2 hours before the sulfanilamide solution is well converted, reducing the phosgene flow until the process requirement cumulant is reached, transferring a product into a light breaking kettleafter heat preservation is performed for 2 hours, removing redundant phosgene by using nitrogen, and finally obtaining a finished product after qualified sampling and analyzing. According to the invention, the synthesis system of sulfonyl isocyanate is optimized, the yield of sulfonyl isocyanate is improved, and meanwhile, the synthesized tail gas and the gas-driving tail gas are innovatively condensed by a condenser and then flow back to the synthesis kettle, so that the tail gas is recycled, and the reaction rate and content of the product are improved.

Eine neue Palladium-katalysierte Carbonylierung von aromatischen N-Chlorsulfonamidaten zu Arylsulfonylisocyanaten

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