64935-39-3Relevant academic research and scientific papers
Visible-Light-Promoted Intramolecular α-Allylation of Aldehydes in the Absence of Sacrificial Hydrogen Acceptors
Liu, Feng,Liu, Jia-Li,tu, Jia-Lin
supporting information, p. 7369 - 7372 (2020/10/05)
We report herein an unprecedented protocol for radical cyclization of aldehydes with pendant alkenes via synergistic photoredox, cobaloxime, and amine catalysis. The transformation was achieved in the absence of external oxidants, providing a variety of 5-, 6-, and 7-membered ring products with alkene transposition in satisfactory yields. The reaction exhibits wide functional group compatibility and occurs under mild conditions with extrusion of H2.
Palladium-catalyzed α-arylation of aldehydes with aryl bromides
Terao, Yoshito,Fukuoka, Yuichi,Satoh, Tetsuya,Miura, Masahiro,Nomura, Masakatsu
, p. 101 - 104 (2007/10/03)
Aliphatic linear and α-branched aldehydes efficiently undergo arylation at the α-position upon treatment with aryl bromides using an appropriate palladium catalyst system that is capable of overcoming aldol condensation of the substrates.
