64951-03-7

Basic information

• Product Name: 1H-Indole-2-acetic acid, 3-formyl-, methyl ester
• Synonyms: methyl 3-formyl-1H-indole-2-acetate;(3-formyl-indol-2-yl)-acetic acid methyl ester;1H-Indole-2-acetic acid,3-formyl-,methyl ester
• CAS NO: 64951-03-7
• Molecular Formula: C12H11NO3
• Molecular Weight: 217.224
• Mol File: 64951-03-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 406.2±30.0 °C(Predicted)
• Density: 1.305±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1H-Indole-2-acetic acid, 3-formyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-acetic acid, 3-formyl-, methyl ester(64951-03-7)
• EPA Substance Registry System: 1H-Indole-2-acetic acid, 3-formyl-, methyl ester(64951-03-7)

Safety Data

• Hazardous Substances Data: 64951-03-7(Hazardous Substances Data)

Upstream product

• 5059-30-3 2-chloroindole-3-carboxaldehyde 

Downstream Products

• 26612-48-6 5,12-dihydrocycloocta[1,2b;5,6b']diindole-6,13-dicarboxylic acid dimethyl ester 
• 1465030-30-1 (E)-methyl α-(3-formyl-1H-indol-2-yl)-β-(4-benzyloxy-3-methoxyphenyl)acrylate 
• 1465030-29-8 (E)-methyl α-(3-formyl-1H-indol-2-yl)-β-(2,5-dimethoxyphenyl)acrylateb 
• 1465030-27-6 (E)-methyl α-(3-formyl-1H-indol-2-yl)-β-(4-methoxyphenyl)acrylate 
• 1465030-25-4 (E)-methyl α-(3-formyl-1H-indol-2-yl)-β-(2-methoxyphenyl)acrylate 
• 1465031-06-4 methyl 3-(4-methylphenyl)-5H-pyrido[4,3-b]indole-4-carboxylate 
• 1465030-22-1 (E)-methyl α-(3-formyl-1H-indol-2-yl)-β-(4-methylphenyl)acrylate 
• 1465030-21-0 (E)-methyl α-(3-formyl-1H-indol-2-yl)-β-(3-methylphenyl)acrylate 
• 1465031-03-1 methyl 3-phenyl-5H-pyrido[4,3-b]indole-4-carboxylate 
• 1465030-20-9 (E)-methyl α-(3-formyl-1H-indol-2-yl)-β-phenylacrylate 
• 1465030-72-1 (E)-methyl α-(3-formyl-1H-indol-2-yl)-β-(2-phenylethyl)acrylate 
• 1465030-74-3 (Z)-methyl α-(3-formyl-1H-indol-2-yl)-β-(2-phenylethyl)acrylate 
• 1465031-18-8 methyl 3-[2-(tert-butoxycarbonyl)aminophenyl]-5H-pyrido[4,3-b]indole-4-carboxylate 
• 1465030-47-0 (E)-methyl α-(3-formyl-1H-indol-2-yl)-β-[2-(tert-butoxycarbonyl)aminophenyl]acrylate 

Relevant articles and documents

Method for simply and efficiently synthesizing caulerpin

The invention belongs to the field of organic chemical synthesis and discloses a method for simply and efficiently synthesizing caulerpin. The method comprises the following steps: by taking 2-indolone as a raw material, firstly, performing halogenated acylation on the 2-indolone, protecting amino on indole, performing nucleophilic substitution at a site 2 of the amino, connecting malonic acid dimethyl, further performing decarboxylation and protection group removal so as to obtain 3-formyl-2-indole methyl acetate, and finally performing cyclization between two molecules, so as to obtain caulerpin. Compared with a disclosed method for synthesizing caulerpin, the method disclosed by the invention is simple in synthesis process, low in raw material cost, gentle in reaction condition, high inproduct purity, high in yield and easy in industrialization, and has a very high medical value and a wide market prospect.