649550-08-3Relevant academic research and scientific papers
Ring closure reactions of 5-azidopyrido[2,3-d]pyrimidinetriones to isoxazolo- and oxadiazolopyrido[2,3-d]pyrimidinetriones
Van Tinh, Dang,Stadlbauer, Wolfgang
, p. 1695 - 1699 (2008)
(Chemical Equation Presented) Thermal decomposition of 5-azidopyrido[2,3-d] pyrimidines 2 and 7 having reactive ortho-substituents such as a formyl or a nitro group yielded isoxazolo[3′,4′:4,5]pyrido[2,3-d]pyrimidines 3 or oxadiazolo-[3′,4′:4,5]pyrido[2,3-d]pyrimidines 9. The reaction conditions of the azide decomposition were studied by differential scanning calorimetry (DSC). In addition, desoxygenation of N-oxides 9 to oxadiazoles 10 and regioselective reduction of azides 7 to amines 8 were studied.
