649554-77-8Relevant academic research and scientific papers
Differentiating the 2,3-diols of glucopyranosides by 4,6-O-benzylidene- protected-1,2-D-glucopyranosylorthoesters strategy
Wang, Guangfa,Lu, Zhichao,Ding, Ning,Zhang, Wei,Wang, Peng,Li, Yingxia
, p. 2368 - 2373 (2011/12/04)
A facile and efficient method to differentiate the 2,3-diols of glucopyranosides based on 1,2-orthoesters strategy was developed. Stable thioglucosides were employed as the starting materials to prepare the corresponding 1,2-orthoesters. When treated with HCl aqueous solution and followed with Et3N, differentiation of the 2,3-diols was efficiently achieved along with the generation of a convertible anomeric hydroxyl group. In addition, an easy and practical method based on NOE was proposed to determine whether the 1,2-orthoesters were endo-type or exo-type.
Synthesis of the β-1,3-glucan, laminarahexaose: NMR and conformational studies
Mo, Kai-For,Li, Huiqing,Mague, Joel T.,Ensley, Harry E.
experimental part, p. 439 - 447 (2009/05/27)
The synthesis of laminarahexaose is described. NMR studies of several of the intermediates leading to the β-1,3-glucan show anomalously small coupling constants for some of the C-1 hydrogens. An X-ray structure for the protected hexasaccharide shows that
Method for synthesis of beta glucans
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Page/Page column 8, (2010/10/20)
The invention provides a method for forming P-glucoside linkages in carbohydrate polymers, particularly synthetic glucan molecules, by attaching a protecting group to the C2 position of a glucoside donor. The protecting group of the invention stabilizes t
An efficient method for the preparation of glycosides with a free C-2 hydroxyl group from thioglycosides
Yu, Hai,Ensley, Harry E.
, p. 9363 - 9366 (2007/10/03)
A new and efficient method to produce glycosides with a free C-2 hydroxyl group through 1,2-acyl group migration which occurs during the hydrolysis of 4,6-benzylidene protected thioglycosides has been developed. The acyl transfer products allow for further elaboration.
