649723-78-4Relevant academic research and scientific papers
Synthesis of Novel D-Seco-Pregnenes
Woelfling, Janos,Magyar, Angela,Schneider, Gyula
, p. 1387 - 1393 (2007/10/03)
A new synthetic route was developed for the preparation of trans-3β-hydroxy-16,17-seco-pregna-5,17(20)-dien-16-al, using Grob fragmentation as the key step. This seco-steroid contains a formyl group and an unsaturated side-chain in a sterically favourable position, and is therefore a promising starting material for the synthesis of novel condensed steroid heterocycles.
