Cas 649736-40-3,L-Leucine, N-[(phenylmethoxy)carbonyl]-, (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1, 2,4]triazin-6-yl]oxy]-1-methylethyl ester

649736-40-3

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Basic information

Product Name: L-Leucine, N-[(phenylmethoxy)carbonyl]-, (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1, 2,4]triazin-6-yl]oxy]-1-methylethyl ester
Synonyms:
CAS NO:649736-40-3
Molecular Formula: C33H36FN5O6
Molecular Weight: 617.677
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: L-Leucine, N-[(phenylmethoxy)carbonyl]-, (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1, 2,4]triazin-6-yl]oxy]-1-methylethyl ester(CAS DataBase Reference)
NIST Chemistry Reference: L-Leucine, N-[(phenylmethoxy)carbonyl]-, (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1, 2,4]triazin-6-yl]oxy]-1-methylethyl ester(649736-40-3)
EPA Substance Registry System: L-Leucine, N-[(phenylmethoxy)carbonyl]-, (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1, 2,4]triazin-6-yl]oxy]-1-methylethyl ester(649736-40-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 649736-40-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 649736-40-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,9,7,3 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 649736-40:
(8*6)+(7*4)+(6*9)+(5*7)+(4*3)+(3*6)+(2*4)+(1*0)=203
203 % 10 = 3
So 649736-40-3 is a valid CAS Registry Number.

649736-40-3Upstream product

649736-40-3Downstream Products

649736-40-3Relevant academic research and scientific papers

Discovery of brivanib alaninate ((S)-((R)-1-(4-(4-fluoro-2-methyl-1H-indol- 5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-yl) 2-aminopropanoate), a novel prodrug of dual vascular endothelial growth factor receptor-2 and fibroblast growth

Cai, Zhen-Wei,Zhang, Yongzheng,Borzilleri, Robert M.,Qian, Ligang,Barbosa, Stephanie,Wei, Donna,Zheng, Xiaoping,Wu, Lawrence,Fan, Junying,Shi, Zhongping,Wautlet, Barri S.,Mortillo, Steve,Jeyaseelan Sr., Robert,Kukral, Daniel W.,Kamath, Amrita,Marathe, Punit,D'Arienzo, Celia,Derbin, George,Barrish, Joel C.,Robl, Jeffrey A.,Hunt, John T.,Lombardo, Louis J.,Fargnoli, Joseph,Bhide, Rajeev S.

, p. 1976 - 1980 (2008/12/22)

A series of amino acid ester prodrugs of the dual VEGFR-2/FGFR-1 kinase inhibitor 1 (BMS-540215) was prepared in an effort to improve the aqueous solubility and oral bioavailability of the parent compound. These prodrugs were evaluated for their ability t

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