649749-10-0

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Basic information

Product Name: ATN-224
Synonyms: ATN-224;Bis(choline)tetrathioMolybdate
CAS NO:649749-10-0
Molecular Formula: C10H28MoN2O2S4
Molecular Weight: 432.54152
EINECS: N/A
Product Categories: N/A
Mol File: 649749-10-0.mol
Article Data: 0

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: ATN-224(CAS DataBase Reference)
NIST Chemistry Reference: ATN-224(649749-10-0)
EPA Substance Registry System: ATN-224(649749-10-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 649749-10-0(Hazardous Substances Data)

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bis-(Choline)tetrathiomolybdate
Cas No: 649749-10-0
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Dayang Chem (Hangzhou) Co.,Ltd.
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ATN 224
Cas No: 649749-10-0
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1 Kilogram
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Shandong Hanjiang Chemical Co., Ltd.
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TIANFUCHEM-ATN 224
Cas No: 649749-10-0
USD $ 3000.0-3000.0 / Metric Ton
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Henan Tianfu Chemical Co., Ltd.
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649749-10-0 CAS NO.649749-10-0
Cas No: 649749-10-0
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KAISA GROUP INC
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649749-10-0
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Changchun Artel lmport and Export trade company
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ATN-224
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ZHEJIANG JIUZHOU CHEM CO.,LTD
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ATN-224
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10 Milligram
Amadis Chemical Co., Ltd.
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ATN-224with factory price
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Wuhan Sun-shine Bio-technology Corporation Limited
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649749-10-0 CAS NO.649749-10-0
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Jilin haofei import and export trade Co.,Ltd
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ATN 224
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Shanghai Haoyuan Chemexpress Co., Ltd.
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649749-10-0 Usage

Description

ATN-224 is a choline salt of tetrathiomolybdate and an inhibitor of superoxide dismutase 1 (SOD1; IC50s = 2.91 and 3.51 μM in human and mouse blood cells, respectively, in vitro). ATN-224 reduces the viability of cultured oxidative stress-resistant WEHI7.2 murine thymic lymphoma cells (EC50s = 5-6 nM) and human diffuse large B cell lymphoma cell lines (EC50s = 9.73-105.61 nM) independently of Bcl-2 and Bcl-xL. In vivo, ATN-224 (0.7 mg/kg) chelates copper to stabilize an antitumor viral vector, enhancing its efficacy against lung metastases in mice. It also inhibits angiogenesis in a mouse model (IC50s = 1.50-3 mg/kg via gavage).

Check Digit Verification of cas no

The CAS Registry Mumber 649749-10-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,9,7,4 and 9 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 649749-10:
(8*6)+(7*4)+(6*9)+(5*7)+(4*4)+(3*9)+(2*1)+(1*0)=210
210 % 10 = 0
So 649749-10-0 is a valid CAS Registry Number.

649749-10-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	bis(sulfanylidene)molybdenum,2-hydroxyethyl(trimethyl)azanium,sulfanide

1.2 Other means of identification

Product number	-
Other names	Bis(choline)tetrathiomolybdate

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

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