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ATN-224 is a choline salt of tetrathiomolybdate and an inhibitor of superoxide dismutase 1 (SOD1), which plays a crucial role in reducing oxidative stress and enhancing the efficacy of antitumor therapies.

649749-10-0

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649749-10-0 Usage

Uses

Used in Anticancer Applications:
ATN-224 is used as an anticancer agent for its ability to reduce the viability of cultured oxidative stress-resistant WEHI7.2 murine thymic lymphoma cells and human diffuse large B cell lymphoma cell lines. It also chelates copper to stabilize an antitumor viral vector, enhancing its efficacy against lung metastases in mice.
Used in Angiogenesis Inhibition:
ATN-224 is used as an angiogenesis inhibitor in a mouse model, demonstrating its potential to inhibit the formation of new blood vessels that supply nutrients to tumors, thus limiting their growth and progression.
Used in Drug Delivery Systems:
Although not explicitly mentioned in the provided materials, ATN-224's potential use in drug delivery systems could be explored to improve its delivery, bioavailability, and therapeutic outcomes in various cancer treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 649749-10-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,9,7,4 and 9 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 649749-10:
(8*6)+(7*4)+(6*9)+(5*7)+(4*4)+(3*9)+(2*1)+(1*0)=210
210 % 10 = 0
So 649749-10-0 is a valid CAS Registry Number.

649749-10-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name bis(sulfanylidene)molybdenum,2-hydroxyethyl(trimethyl)azanium,sulfanide

1.2 Other means of identification

Product number -
Other names Bis(choline)tetrathiomolybdate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:649749-10-0 SDS

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