64977-43-1Relevant academic research and scientific papers
Palladium-catalyzed direct mono-α-arylation of α-fluoroketones with aryl halides or phenyl triflate
Zhou, Jun,Fang, Xiang,Shao, Tongle,Yang, Xueyan,Wu, Fanhong
, p. 54 - 62 (2016/10/05)
A palladium catalyzed Negishi-type α-arylation of α-fluoroketones with electron-rich and electron-deficient aryl halides or phenyl triflate has been developed. This direct mono-α-arylation method generate a variety of ternary α-aryl-α-monofluoroketones easily in good to excellent yields using XPhos as ligand and Cs2CO3as mild base.
