64984-11-8Relevant academic research and scientific papers
Styrylsulfonamides
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Page/Page column 17, (2010/11/24)
The present invention relates to the compounds of formula I: their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above compounds, pharmaceutical compositions containing them and the
Synthesis of E-aryl ethenesulfonamides: A simple one-pot, two-step procedure from 1-hydroxy-1-arylalkanes
Aramini, Andrea,Cesta, Maria C.,Coniglio, Silvia,Bijani, Christian,Colagioia, Sandro,D'Elia, Valerio,Allegretti, Marcello
, p. 7911 - 7914 (2007/10/03)
The unusual reactivity of 1-phenyl-1-ethane-sulfonic acid in thionyl chloride was investigated. Mechanistic considerations led us to set up a new and efficient synthesis of E-arylethenesulfonamides starting from 1-hydroxy-1-arylalkanes. The easy availability of the starting materials and the straightforward, one-pot procedure make this process an attractive method for the preparation of these compounds currently largely employed in chemical and pharmaceutical fields.
Synthesis of Vinyl Sulfonamides Using the Horner Reaction
Reuter, Deborah C.,McIntosh, Joel E.,Guinn, Ashley C.,Madera, Ann Marie
, p. 2321 - 2324 (2007/10/03)
A series of vinyl sulfonamides was synthesized using the Horner reaction of aldehydes and diphenylphosphorylmethane-sulfonamide. The sulfonamide reagent was easily prepared and can be stored indefinitely. The trans orientation about the double bond of the vinyl sulfonamides was the only isomer observed.
