64987-84-4

Basic information

• Product Name: 4-(2-N-Maleimido)methyl benzoic acid-NHS
• Synonyms: 4-(2-N-Maleimido)methyl benzoic acid-NHS;4-(MaleiMidoMethyl)-benzoic acid-NHS ester;2,5-dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)benzoate;4-Mal-MBz-NHS
• CAS NO: 64987-84-4
• Molecular Formula: C16H12N2O6
• Molecular Weight: 328.27628
• Mol File: 64987-84-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(2-N-Maleimido)methyl benzoic acid-NHS(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-N-Maleimido)methyl benzoic acid-NHS(64987-84-4)
• EPA Substance Registry System: 4-(2-N-Maleimido)methyl benzoic acid-NHS(64987-84-4)

Safety Data

• Hazardous Substances Data: 64987-84-4(Hazardous Substances Data)

Usage

General Description

4-(2-N-Maleimido)methyl benzoic acid-NHS is a chemical compound primarily used in bioconjugation reactions for the attachment of maleimide-functionalized molecules to primary amines on proteins and peptides. It consists of a maleimide group, which readily reacts with thiol groups in proteins to form stable thioether linkages, and a N-hydroxysuccinimide (NHS) ester, which allows for easy coupling to amine groups. 4-(2-N-Maleimido)methyl benzoic acid-NHS is often utilized in the development of targeted drug delivery systems, imaging agents, and immunodiagnostic assays, as well as in the modification of surfaces for various biological applications. Its versatile reactivity and stability make it a valuable tool in chemical biology and biomedical research.