64989-46-4

Basic information

• Product Name: ETHYL 2-CHLORO-2-[2-(2-METHYLPHENYL)HYDRAZONO]-ACETATE
• Synonyms: ETHYL 2-CHLORO-2-[2-(2-METHYLPHENYL)HYDRAZONO]-ACETATE;Ethyl 2-chloro-2-[2-(2-methylphenyl)hydrazono)-;Ethyl chloro[(2-methylphenyl)hydrazono]acetate;ethyl (2Z)-2-chloro-2-[2-(2-methylphenyl)hydrazin-1-ylidene]acetate
• CAS NO: 64989-46-4
• Molecular Formula: C₁₁H₁₃ClN₂O₂
• Molecular Weight: 240.69
• Mol File: 64989-46-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 319.5°C at 760 mmHg
• Flash Point: 147°C
• Appearance: /
• Density: 1.19g/cm³
• Vapor Pressure: 0.000337mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: ETHYL 2-CHLORO-2-[2-(2-METHYLPHENYL)HYDRAZONO]-ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-CHLORO-2-[2-(2-METHYLPHENYL)HYDRAZONO]-ACETATE(64989-46-4)
• EPA Substance Registry System: ETHYL 2-CHLORO-2-[2-(2-METHYLPHENYL)HYDRAZONO]-ACETATE(64989-46-4)

Safety Data

• Hazardous Substances Data: 64989-46-4(Hazardous Substances Data)

Usage

General Description

ETHYL 2-CHLORO-2-[2-(2-METHYLPHENYL)HYDRAZONO]-ACETATE, also known as 2-chloro-2-(2-methylphenyl)hydrazonoethanoic acid ethyl ester, is a chemical compound with the molecular formula C11H13ClN2O2. It is a yellow to brown crystalline powder that is used in various chemical and pharmaceutical applications. ETHYL 2-CHLORO-2-[2-(2-METHYLPHENYL)HYDRAZONO]-ACETATE is commonly used as a reagent in organic synthesis, specifically in the preparation of various hydrazones. It is also used as a precursor in the production of pharmaceuticals and agrochemicals. Additionally, it has been studied for its potential applications in medicinal chemistry, particularly for its antibacterial and antifungal properties. Overall, ETHYL 2-CHLORO-2-[2-(2-METHYLPHENYL)HYDRAZONO]-ACETATE is a versatile compound with numerous potential uses in the fields of chemistry and pharmacology.

InChI:InChI=1/C11H13ClN2O2/c1-3-16-11(15)10(12)14-13-9-7-5-4-6-8(9)2/h4-7,13H,3H2,1-2H3/b14-10+

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Relevant articles and documents

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The invention relates to a quinoline derivative shown as the general formula I and containing 2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one and imidazole, and pharmaceutically acceptable salt, hydrate, solvate or prodrug of the quinoline derivative. In the general formula I, Ar, R1, R2, L, and n have meanings as the description defined. The invention further relates to a great c-Met kinase inhibiting effect of the compound shown as the general formula I, and applications of pharmaceutically acceptable salt, hydrate, solvate or prodrug of the compound to prepare medicines for treating and/or preventing diseases caused by abnormal high expression of c-Met kinase, particularly an application of preparing a medicine for treating and/or preventing cancer.