65001-79-8

Basic information

• Product Name: 5-Chloro-4-fluoro-2-nitrophenol
• Synonyms: 5-Chloro-4-fluoro-2-nitrophenol
• CAS NO: 65001-79-8
• Molecular Formula: C6H3ClFNO3
• Molecular Weight: 192
• Mol File: 65001-79-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-Chloro-4-fluoro-2-nitrophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-4-fluoro-2-nitrophenol(65001-79-8)
• EPA Substance Registry System: 5-Chloro-4-fluoro-2-nitrophenol(65001-79-8)

Safety Data

• Hazardous Substances Data: 65001-79-8(Hazardous Substances Data)

Usage

General Description

5-Chloro-4-fluoro-2-nitrophenol is a chemical compound with the molecular formula C6H3ClFNO4. It is a yellow solid with a molecular weight of 191.54 g/mol. 5-Chloro-4-fluoro-2-nitrophenol is used in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a reagent for the determination of copper in environmental water samples. Additionally, 5-Chloro-4-fluoro-2-nitrophenol has antibacterial and antifungal properties, making it effective in certain medical and agricultural applications. However, it is important to handle this compound with caution due to its potential toxicity and environmental impact.

Upstream product

• 2613-23-2 3-chloro-4-fluorophenol 

Relevant articles and documents

Design, synthesis, and cytotoxicity of 5-fluoro-2-methyl-6-(4-aryl-piperazin-1-yl) benzoxazoles

To design new compounds suitable as starting points for anticancer drug development, we have synthesized a novel series of benzoxazoles with pharmaceutically advantageous piperazine and fluorine moieties attached to them. The newly synthesized benzoxazoles and their corresponding precursors were evaluated for cytotoxicity on human A-549 lung carcinoma cells and non-cancer HepaRG hepatocyes. Some of these new benzoxazoles show potential anticancer activity, while two of the intermediates show lung cancer selective properties at low concentrations where healthy cells are unaffected, indicating a selectivity window for anticancer compounds.