65017-66-5Relevant academic research and scientific papers
ASYMMETRIC SYNTHESES IV: ENANTIOSELECTIVE SYNTHESIS OF (R)-BENZYLIC AMINES VIA ALKYLATION OF D-CAMPHOR KETIMINE
Yaozhong, Jiang,Guilan, Liu,Jinchu, Liu,Changyou, Zhou
, p. 1545 - 1548 (2007/10/02)
An efficient asymmetric synthesis of (R)-benzylic amines in optical purity 36-90percent had been achieved by alkylation of a chiral ketimine prepared from D-camphor and benzylamine.Diastereoselectivity in the alkylation is dependent on the alkyl halides.
Synthesis and structure-activity relationships of 1-substituted 4-(1,2-diphenylethyl)piperazine derivatives having narcotic agonist and antagonist activity
Natsuka,Nakamura,Nishikawa,Negoro,Uno,Nishimura
, p. 1779 - 1787 (2007/10/02)
Racemates and enantiomers of 1-substituted 4-[2-(3-hydroxyphenyl)-1-phenylethyl]piperazine derivatives (3-18) were synthesized, and their analgesic and other pharmacological activities and structure-activity relationships were investigated. The S-(+) enan
