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3-(2-hydroxy-4-methoxyphenyl)-7,8-dimethoxy-4H-chromen-4-one is a complex organic compound belonging to the class of flavonoids, specifically flavones. It is characterized by a chromen-4-one core structure, which is a type of chromone with a double bond between carbons 2 and 3. The molecule features a hydroxyl group at the 2-position and a methoxy group at the 4-position of the phenyl ring attached at the 3-position of the chromen-4-one. Additionally, it has two methoxy groups at the 7 and 8 positions of the chromen-4-one ring. 3-(2-hydroxy-4-methoxyphenyl)-7,8-dimethoxy-4H-chromen-4-one is known for its potential antioxidant and anti-inflammatory properties, and it can be found in various plants, contributing to their medicinal and nutritional value.

6502-89-2

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6502-89-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6502-89-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,5,0 and 2 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6502-89:
(6*6)+(5*5)+(4*0)+(3*2)+(2*8)+(1*9)=92
92 % 10 = 2
So 6502-89-2 is a valid CAS Registry Number.

6502-89-2Downstream Products

6502-89-2Relevant academic research and scientific papers

Synthesis, optical resolution, absolute configuration, and osteogenic activity of cis-pterocarpans

Goel, Atul,Kumar, Amit,Hemberger, Yasmin,Raghuvanshi, Ashutosh,Jeet, Ram,Tiwari, Govind,Knauer, Michael,Kureel, Jyoti,Singh, Anuj K.,Gautam, Abnish,Trivedi, Ritu,Singh, Divya,Bringmann, Gerhard

, p. 9583 - 9592 (2013/01/16)

A convenient synthesis of natural and synthetic pterocarpans was achieved in three steps. Optical resolution of the respective enantiomers was accomplished by analytical and semi-preparative HPLC on a chiral stationary phase. For medicarpin and its synthetic derivative 9-demethoxymedicarpin, the absolute configuration was confirmed by a combination of experimental LC-ECD coupling and quantum-chemical ECD calculations. (-)-Medicarpin and (-)-9-demethoxymedicarpin are both 6aR,11aR-configured, and consequently the corresponding enantiomers, (+)-medicarpin and (+)-9-demethoxymedicarpin, possess the 6aS,11aS-configuration. A comparative mechanism study for osteogenic (bone forming) activity of medicarpin (racemic versus enantiomerically pure material) revealed that (+)-(6aS,11aS)-medicarpin (6a) significantly increased the bone morphogenetic protein-2 (BMP2) expression and the level of the bone-specific transcription factor Runx-2 mRNA, while the effect was opposite for the other enantiomer, (-)-(6aR,11aR)-medicarpin (6a), and for the racemate, (±)-medicarpin, the combined effect of both the enantiomers on transcription levels was observed. The Royal Society of Chemistry 2012.

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