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65025-95-8

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  • (3AR,4S,5R,6AS)-()-(TERT-BUTYLDIMETHYLSILYLOXYMETHYL)HEXAHYDRO-5-(TETRAHYDRO-2H-PYRAN-2-YLOXY)-2H-CYCLOPENTA[B]FURAN-2-ONE

    Cas No: 65025-95-8

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  • High Quality 2H-Cyclopenta[b]furan-2-One,4-[[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy] Methyl]Hexahydro-5-[(Tetrahydro-2H-Pyran-2-yl)Oxy]-,(3aR,4S,5R,6aS)- on stock

    Cas No: 65025-95-8

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  • (3aR,4S,5R,6aS)-4-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]hexahydro-5-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-cyclopenta[b]furan-2-one

    Cas No: 65025-95-8

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65025-95-8 Usage

Uses

Intermediate in the preparation of prostaglandin derivatives

Check Digit Verification of cas no

The CAS Registry Mumber 65025-95-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,0,2 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 65025-95:
(7*6)+(6*5)+(5*0)+(4*2)+(3*5)+(2*9)+(1*5)=118
118 % 10 = 8
So 65025-95-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H34O5Si/c1-19(2,3)25(4,5)22-12-14-13-10-17(20)23-15(13)11-16(14)24-18-8-6-7-9-21-18/h13-16,18H,6-12H2,1-5H3/t13-,14-,15+,16-,18?/m1/s1

65025-95-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (3aR,4S,5R,6aS)-4-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(oxan-2-yloxy)-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one

1.2 Other means of identification

Product number -
Other names Corey lactone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:65025-95-8 SDS

65025-95-8Relevant articles and documents

Discovery of novel seven-membered prostacyclin analogues as potent and selective prostaglandin FP and EP3 Dual Agonists

Sugimoto, Isamu,Kambe, Tohru,Okino, Tomotaka,Obitsu, Tetsuo,Ohta, Nobukazu,Nishiyama, Taihei,Kinoshita, Akihiro,Fujimoto, Taku,Egashira, Hiromu,Yamane, Shinsaku,Shuto, Satoshi,Tani, Kousuke,Maruyama, Toru

supporting information, p. 107 - 112 (2017/12/12)

A novel series of prostaglandin analogues with a seven-membered ring scaffold was designed, synthesized, and evaluated for the functional activation of prostaglandin receptors to identify potent and subtype-selective FP and EP3 dual agonists. Starting fro

A process for the preparation of intermediates useful in the ruby's forefront, preparation method thereof and through its preparation ruby's forefront method

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Paragraph 0062-0064, (2017/08/03)

The invention relates to an intermediate for preparing lubiprostone, a preparation method of the intermediate and a method for preparing the lubiprostone through the intermediate, in particular to a compound as shown in a formula V for preparing the lubiprostone (as shown in a formula I), a preparation method of the compound and a method for preparing the lubiprostone through the compound. The method comprises the following steps: performing reduction treatment on the compound as shown in the formula V, performing selective deprotection and hydroxyl oxidation to obtain a compound as shown in a formula II, and performing hydroxyl deprotection on the compound as shown in the formula II to prepare the lubiprostone as shown in the formula I. The method is easy and convenient to operate, high in synthetic yield and suitable for large-scale production.

BICYCLIC COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES

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Paragraph 0173-0175, (2013/12/03)

Provided is a compound which has strong intraocular pressure lowering action and has no side effect on eyes such as ocular stimulating property, humor protein rise etc. Since a compound represented by the formula (I): (wherein definition of each group is

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