6504-13-8

Basic information

• Product Name: 4-(1H-BENZOIMIDAZOL-2-YL)-PHENOL
• Synonyms: 4-(1H-benzimidazol-2-yl)phenol(SALTDATA: 0.2H2O);4-(1H-benzimidazol-2-yl)phenol 0.2H2O;4-(1H-benzo[d]iMidazol-2-yl)phenol;4-(1H-Benzo[d]imidazol-2-yl)phenol hydrochloride;2-(4-hydroxyphenyl)benzimidazole
• CAS NO: 6504-13-8
• Molecular Formula: C₁₃H₁₀N₂O
• Molecular Weight: 246.7
• Mol File: 6504-13-8.mol
• Article Data: 142

Chemical Properties

• Boiling Point: 462.828°C at 760 mmHg
• Flash Point: 233.71°C
• Appearance: /
• Density: 1.324g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.726
• CAS DataBase Reference: 4-(1H-BENZOIMIDAZOL-2-YL)-PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1H-BENZOIMIDAZOL-2-YL)-PHENOL(6504-13-8)
• EPA Substance Registry System: 4-(1H-BENZOIMIDAZOL-2-YL)-PHENOL(6504-13-8)

Safety Data

• Hazardous Substances Data: 6504-13-8(Hazardous Substances Data)

Usage

General Description

4-(1H-BENZOIMIDAZOL-2-YL)-PHENOL, also known as HBBIP, is a chemical compound with the molecular formula C13H10N2O. It is a phenolic compound that contains a benzimidazole ring, which makes it an important building block for the synthesis of various drugs and bioactive molecules. HBBIP has been studied for its potential anti-inflammatory and antioxidant properties, and it has shown promising results in inhibiting certain enzymes involved in inflammation and oxidative stress. 4-(1H-BENZOIMIDAZOL-2-YL)-PHENOL has also been investigated for its potential use in the treatment of neurodegenerative diseases and cancer. Overall, 4-(1H-BENZOIMIDAZOL-2-YL)-PHENOL has garnered attention for its diverse pharmacological activities and potential applications in drug development.

InChI:InChI=1/C13H10N2O/c16-10-7-5-9(6-8-10)13-14-11-3-1-2-4-12(11)15-13/h1-8,16H,(H,14,15)

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 99-96-7 4-hydroxy-benzoic acid 
• 767-00-0 4-cyanophenol 
• 123-08-0 4-hydroxy-benzaldehyde 
• 5344-90-1 2-Aminobenzyl alcohol 
• 28144-70-9 anthranilic acid amide 
• 3179-08-6 4-(2-nitrovinyl)phenol 
• 107496-03-7 Carbamic acid 4-((E)-2-nitro-vinyl)-phenyl ester 
• 615-28-1 o-phenylenediamine dihydrochloride 
• 69116-33-2 1,2-bis-(4-propoxy-benzoylamino)-benzene 
• 591-31-1 3-methoxy-benzaldehyde 
• 6554-98-9 trans-4-Hydroxystilbene 
• 38148-63-9 p-amidinophenol hydrochloride 
• 1493-27-2 ortho-nitrofluorobenzene 

Downstream Products

• 2620-82-8 1-methyl-2-(4-methoxyphenyl)-1H-benzimidazole 
• 1148018-30-7 C₁₉H₁₃N₃O₂ 
• 47160-86-1 2-[4-(1H-benzo[d]imidazol-2-yl)phenoxy]-N,N-dimethylethanamine 
• 17926-03-3 2-[4-(1H-benzo[d]imidazol-2-yl)phenoxy]-N,N-diethylethanamine 
• 1449214-96-3 N-{2-[4-(1H-benzo[d]imidazol-2-yl)phenoxy]ethyl}-N-isopropylpropan-2-amine 
• 1449214-97-4 2-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-1H-benzo[d]imidazole 
• 1379113-11-7 2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1H-benzo[d]imidazole 
• 1449214-98-5 4-{2-[4-(1H-benzo[d]imidazol-2-yl)phenoxy]ethyl}morpholine 

Relevant articles and documents

Systemic study on fluorescent switching systems composed of naphthopyran and benzimidazole in solution and film forms

The fluorescent photo-switching systems were prepared based on fluorescent benzimidazole and photochromic naphthopyran. Naphthopyran in this systems displayed excellent photochromic performance in tetrahydrofuran solutions and in PMMA films. The fluoresce

Stability constants of Ni(II)- and Cu(II)-N-heterocycle complexes according to spectrophotometric data

The interaction of Ni(II) and Cu(II) with ethyl 4-(4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine- 5-carboxylate [Ligand 1], 4-(1H-benzimidazol-2-yl)phenol [Ligand 2], and 2-(3-phenylamino- 4,5-dihydro-1,2-oxazol-5-yl)phenol [Ligand 3] have been studied by spectrophotometric technique at 0.01 M ionic strength and 28°C in 70% dioxane - water mixture. The data obtained were used to estimate the stability constant of these ligands. Spectrophotometric investigation of Ni(II) and Cu(II) complexes with these ligands shows 1: 1 complex formation. The formation of complexes has been studied by Job's variation method. The values of conditional stability constants of Cu(II) complexes are greater than the corresponding Ni(II) complexes. The greater value of stability constant of Cu(II) complexes may be due to the fact of more stable nature of Cu(II). The value of stability constant of Cu(II) - Ligand 2 complex is greater than that of Cu(II)-Ligand 1 and Cu(II)-Ligand 3. The same of Ni(II)-Ligand 3 complex is greater than that of Ni(II)-Ligand 1 and Ni(II)-Ligand 2.

Design, preparation, biological investigations and application of a benzoguanamine-based nickel complex for the synthesis of benzimidazoles

The new magnetic-supported benzoguanamine-based nickel complex was prepared, characterized by various procedures and used as a capable heterogeneous nano-catalyst for the synthesis of diverse 2-phenyl-1H-benzo[d]imidazoles from the reaction o-phenylenedia

Tetrathienoanthracene-functionalized conjugated microporous polymers as an efficient, metal-free visible-light solid organocatalyst for heterogeneous photocatalysis

Owing to their advantages of superior inherent porosity, high chemical stability, light weight, and molecularly tunable optoelectronic properties, conjugated microporous polymers (CMPs) have been receiving increasing attention and research interest as pro