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65053-26-1

65053-26-1

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65053-26-1 Usage

Chemical Properties

Brown Solid

Uses

4-(2-Aminoanilino)pyridine is an intermediate used to prepare Timiperone as well as cyclooxygenase-2 inhibitors and adrenergic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 65053-26-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,0,5 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 65053-26:
(7*6)+(6*5)+(5*0)+(4*5)+(3*3)+(2*2)+(1*6)=111
111 % 10 = 1
So 65053-26-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H11N3/c12-10-3-1-2-4-11(10)14-9-5-7-13-8-6-9/h1-8H,12H2,(H,13,14)

65053-26-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-N-pyridin-4-ylbenzene-1,2-diamine

1.2 Other means of identification

Product number -
Other names N1-4-Pyridinyl-1,2-benzenediamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:65053-26-1 SDS

65053-26-1Relevant articles and documents

Synthesis and Characterization of Water-Soluble and Photolabile 10-Arylisoalloxazines: Tools for Studying the Mechanism of Action of Flavin-Type Antimalarials

Kirsch, Peer,Schoenleben-Janas, Annette,Schirmer, R. Heiner

, p. 1275 - 1282 (2007/10/02)

Isoalloxazine derivatives such as 1a-d are promising antimalarial agents which act as inhibitors of the antioxidant enzyme glutathione reductase and possibly of other proteins.The molecular mechanism of the pharmacological effects has not been studied in detail because compounds 1a-d are poorly soluble in aqueous solutions of physiological pH.In the present study we introduce two new types of isoalloxazine derivatives with improved solubility properties.The 10-aryl-3-carboxymethylisoalloxazines 2a-d, and the isomeric 3-methyl-10-(N-methylpyridiniumyl)isoalloxazine salts 3 and 4.In addition, for the purpose of photoaffinity labeling experiments, the 10-aryl-8-azido-3-methylisoalloxazine 5 was designed.The syntheses and characterizations of these new flavins as well as an alternative synthetic approach to the known antimalarials 1a-d are described. - Keywords: Flavins/Isoalloxazines/Arylisoalloxazines/Malaria/Antimalarials/Glutathione reductase inhibitors/Photoaffinity labels

Method of Treating Senile Cognitive Decline with N'-substituted Aminopyridine Adrenergic Agents

-

, (2008/06/13)

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