650602-49-6

Basic information

• Product Name: 1,3-Pentanedione, 2-fluoro-4,4-dimethyl-1-phenyl-
• CAS NO: 650602-49-6
• Molecular Formula: C13H15FO2
• Molecular Weight: 222.259
• Mol File: 650602-49-6.mol

Chemical Properties

• CAS DataBase Reference: 1,3-Pentanedione, 2-fluoro-4,4-dimethyl-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Pentanedione, 2-fluoro-4,4-dimethyl-1-phenyl-(650602-49-6)
• EPA Substance Registry System: 1,3-Pentanedione, 2-fluoro-4,4-dimethyl-1-phenyl-(650602-49-6)

Safety Data

• Hazardous Substances Data: 650602-49-6(Hazardous Substances Data)

Upstream product

• 61317-72-4 4,4-dimethylpent-1-yn-3-ol 
• 13988-67-5 benzoylpivaloylmethane 

Downstream Products

• 1328920-98-4 3-tert-butyl-4-fluoro-5-phenyl-1H-pyrazole 

Relevant articles and documents

Gold-catalyzed Fluorination of Alkynyl Esters and Ketones: Efficient Access to Fluorinated 1,3-Dicarbonyl Compounds

We developed an efficient synthesis of 2-fluoro-1,3-dicarbonyl compounds using readily available alkynyl ketones or esters as starting material. The key step is the insertion of hydrogen fluoride (HF) to the gold carbene intermediate generated from cationic gold catalyzed addition of N-oxides to alkynyl ketones or esters. This method gives excellent chemical yields and regioselectivity with good functional group tolerance. (Figure presented.).

Continuous gas/liquid-liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination

4-Fluoropyrazole systems may be prepared by a single, sequential telescoped two-step continuous gas/liquid-liquid/liquid flow process from diketone, fluorine gas and hydrazine starting materials.