650616-80-1Relevant academic research and scientific papers
Periphery-modified crown ethers. Synthesis of bis-5,8-dimethoxy-1,4- methanonaphthalene-fused crown ethers
Chou, Teh-Chang,Chen, Shing-Yi,Chen, Yie-Hsung
, p. 9939 - 9950 (2003)
The easily accessible and multi-functionalized 5,8-dimethoxy-6,7-dihydroxy methyl-1,4-dihydro-1,4-methanonaphthalene (1) has been utilized as the basic building material to synthesize the symmetric bis-methanonaphthalene-fused crown ethers 14a-d (BMN-16-crown-4, BMN-22-crown-6, BMN-28-crown-8, and BMN-34-crown-10), that are constructed based on the connection between the α,β-bis-benzylic carbon atoms of diol 1 and oligoethylene glycols (9a-d) via two synthetic routes keyed upon the method of Williamson ether synthesis.
