6508-43-6

Usage

Uses

Used in Pharmaceutical Industry:
5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE is used as a pharmaceutical compound for its potential therapeutic effects. Its unique structure allows it to interact with specific biological targets, making it a promising candidate for the development of new drugs.
Used in Chemical Research:
In the field of chemical research, 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE serves as a valuable compound for studying its chemical properties, reactivity, and potential applications in various chemical processes.
Used in Material Science:
5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE may be utilized in material science for the development of novel materials with specific properties. Its unique molecular structure could contribute to the creation of advanced materials with applications in various industries.
Used in Dye and Pigment Industry:
Due to its characteristic color and stability, 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE can be used as a dye or pigment in the textile, paint, or printing industries. Its ability to impart color and its resistance to fading make it a valuable addition to these markets.
Used in Anticancer Applications (based on the provided material for L-152,804):
Although not directly mentioned for 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE, compounds with similar structures may have potential applications in the development of anticancer drugs. Further research would be required to explore this possibility.

Biological Activity

Potent, selective non-peptide neuropeptide Y Y 5 receptor antagonist (K i = 26 nM for hY 5 ). Displays > 300-fold selectivity over hY 1 , hY 2 , and hY 4 receptors. Causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure. Centrally active upon oral administration in vivo .

InChI:InChI=1/C23H26O4/c1-22(2)9-14(24)20(15(25)10-22)19-13-7-5-6-8-17(13)27-18-12-23(3,4)11-16(26)21(18)19/h5-8,19,24H,9-12H2,1-4H3/t19-/m1/s1

Upstream product

• 89-95-2 2-methyl-benzyl alcohol 
• 126-81-8 dimedone 
• 120-72-9 indole 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1112098-24-4 9-(1-bromo-4,4-dimethyl-2,6-dioxocyclohexan-1-yl)-3,3-dimethyl-1,2,3,4-tetrahydro-9H-xanthen-1-one 
• 1112098-26-6 2,4-dibromo-5a-hydroxy-3,3,7,7-tetramethyl-2,3,4,5a,6,7,8,13b-octahydro-1H-chromeno[2,3,4-kl]xanthen-1-one 
• 1112098-28-8 2,4-dibromo-5a-isopropoxy-3,3,7,7-tetramethyl-2,3,4,5a,6,7,8,13b-octahydro-1H-chromeno[2,3,4-kl]xanthen-1-one 

Relevant academic research and scientific papers

Synthesis of fused derivatives of 4,7-phenanthroline by condensation of 6-aminoquinoline with aromatic aldehydes and dimedone

8-Aryl-11,11-dimethyl-7,8,9,10,11,12-hexahydrobenzo[a]phenanthrolin-9-ones were obtained by condensation of 6-aminoquinoline with aromatic aldehydes and dimedone.

An efficient one-pot organocatalytic synthesis of 9-(1H-indol-3-yl)- xanthen-4-(9H)-ones under mild aqueous micellar conditions

An efficient and facile l-proline-catalyzed three-component coupling of 2-hydroxybenzaldehyde, 5,5-dimethyl-1,3-cyclohexanedione (dimedone), and indole has been accomplished under mild aqueous micellar conditions to deliver a small library of 9-(1H-indol-

Neuropeptide Y receptor antagonist

The present invention relates to a neuropeptide Y receptor antagonist comprising a compound represented by the formula [I]: as an active ingredient.

Synthesis of tetra- and octahydroxanthene derivatives by the condensation of dimedone with aromatic aldehydes

The reaction of dimedone with salicyl and 2-hydroxy-1-naphthoyl aldehydes gave derivatives of tetrahydroxanthene and tetrahydrobenzo[a]xanthene and not aldimedone as occurs in condensations with other aldehydes. Derivatives of decahydroacridine were obtained by reaction of the tetrahydroxanthene derivatives with methyl-and ethylamine. Tetrahydro- and octahydroxanthene derivatives were obtained from the reaction of acetylsalicylaldehyde with dimedone in acetic anhydride. The structures of the ketoenol forms of the products containing a β-ketoenol unit were determined by 1H and 13C NMR spectroscopy, and the mechanism of their interconversion is discussed. 1997 Plenum Publishing Corporation.