65080-78-6Relevant academic research and scientific papers
Intramolecular azide-alkene 1,3-dipolar cycloaddition/enamine addition(s) cascade reaction: Synthesis of nitrogen-containing heterocycles
De Miguel, Irene,Herradon, Bernardo,Mann, Enrique
supporting information; experimental part, p. 1731 - 1736 (2012/07/28)
A cascade intramolecular azide-alkene 1,3-dipolar cycloaddition/1,2 enamine and/or 1,4 enamine addition reaction sequence has been developed, and provides access to a variety of nitrogen containing heterocycles from readily available ω-azido alkenes. Copy
REACTION OF METHYL-SUBSTITUTED 7-CHLORO- AND 7,7-DICHLOROBICYCLOheptan-2-ones WITH SODIUM METHOXIDE AND THIOPHENOLATE
Kulinkovich, O. G.,Tishchenko, I. G.,Romashin, Yu. N.
, p. 81 - 85 (2007/10/02)
The reaction of exo-7-chloro-6-methylbicycloheptan-2-one, exo-7-chloro-4,4,6-trimethylbicycloheptan-2-one, 7,7-dichloro-6-methylbicyclo-heptan-2-one, and 7,7-dichloro-4,4,6-trimethylbicycloheptan-2-one with sodium methoxide takes place with opening of the cyclopropane ring and the formation of the corresponding 3-dimethoxymethyl- and 3-trimethoxymethylcyclohexanones.The reaction with sodium thiophenolate leads to the product from substitution of the exo-chlorine atom by the phenylthio group with retention of the three-membered ring.
