65085-95-2Relevant academic research and scientific papers
Efficient Multigram Approach to Acetylenes and CF3-ynones Starting from Dichloroalkenes Prepared by Catalytic Olefination Reaction (COR)
Muzalevskiy, Vasiliy M.,Sizova, Zoia A.,Diusenov, Arstan I.,Shastin, Alexey V.,Nenajdenko, Valentine G.
, p. 4161 - 4166 (2020)
A novel approach to terminal acetylenes based on catalytic olefination reaction COR of arylaldehydes to form dichloroalkenes followed by treatment with nBuLi was elaborated. This method is atom economical and displays high yields and effectivity. The corresponding alkynes can be prepared in up to 97 % yield. One pot procedure towards CF3-ynones was elaborated to provide these products in up to 87 % yield starting from dichloroalkenes.
Visible-Light-Mediated Z -Stereoselective Monoalkylation of β,β-Dichlorostyrenes by Photoredox/Nickel Dual Catalysis
Abdellaoui, Mehdi,Millanvois, Alexandre,Levernier, Etienne,Ollivier, Cyril,Fensterbank, Louis
supporting information, p. 1513 - 1518 (2021/02/26)
Metal-catalyzed alkylation of 1,1-dihalovinyl moiety commonly suffers from both a lack of stereoselectivity and the overreaction leading to the dialkylation product. The methodology described herein features a new pathway to alkylate stereoselectively β,β-dichlorostyryl substrates to provide the Z -trisubstituted olefin only with fair to good yields. This cross-coupling reaction bears on the smooth and photoinduced formation of a C-centered radical that engages in a nickel-catalyzed organometallic cycle to form the key C sp2-C sp3bond.
Reduction of trihalomethyl carbinols and their acetates, mesylates and tosylates by indium metal
Ranu, Brindaban C.,Samanta, Sampak,Das, Arijit
, p. 5993 - 5995 (2007/10/03)
A study of reduction of trihalomethyl carbinols and their derivatives by indium metal shows that while trichloromethyl carbinols produce a mixture of the corresponding dichloromethyl carbinol and vinylidene dichloride, the acetates, mesylates and tosylate
Conversion of aromatic aldehydes into 1-aryl-2,2-dichloroethenes
Nenajdenko,Shastin,Korotchenko,Balenkova
, p. 1047 - 1050 (2007/10/03)
A new general one-pot preparative method for the synthesis of 1-aryl(hetaryl)-2,2-dichloroethenes from aldehydes was developed. The method involves successive conversions of the latter into hydrazones followed by treatment with carbon tetrachloride in the
