651023-32-4Relevant academic research and scientific papers
Rapid synthesis of CDP840 with 2-pyrimidyl vinyl sulfide as a platform
Muraoka, Nobuhiro,Mineno, Masahiro,Itami, Kenichiro,Yoshida, Jun-Ichi
, p. 6933 - 6936 (2005)
A rapid synthesis of CDP840 (a potential therapeutic agent for asthma), using 2-pyrimidyl vinyl sulfide as a platform, has been established. This method includes a stereoselective double Mizoroki-Heck-type arylation, a Liebeskind-Srogltype cross-coupling reaction, and a Pd/C-catalyzed hydrogenation.
