65118-38-9

Basic information

• Product Name: N-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]glycyl-L-glutamic acid
• CAS NO: 65118-38-9
• Molecular Formula: C₂₂H₂₅N₉O₆
• Molecular Weight: 511.4906
• Mol File: 65118-38-9.mol
• Article Data: 1

Chemical Properties

• Density: 1.528g/cm³
• Refractive Index: 1.717
• CAS DataBase Reference: N-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]glycyl-L-glutamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]glycyl-L-glutamic acid(65118-38-9)
• EPA Substance Registry System: N-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]glycyl-L-glutamic acid(65118-38-9)

Safety Data

• Hazardous Substances Data: 65118-38-9(Hazardous Substances Data)

Relevant articles and documents

Potential anticancer agents. 17. Analogues of methotrexate with a tripeptide side chain

Nine tripeptide analogues of methotrexate were synthesized from 2,4 diamino 6 (chloromethyl)pteridine. Only N [N [4 (2,4 diamino 6 pteridinyl)methyl]amino]benzoyl]glycyl DL aspartic acid (la) showed moderate activity against L1210 murine leukemia (ILS = 69%) and W 256 carcinosarcoma TGI = 55%).