65124-89-2

Usage

Uses

Used in Pharmaceutical Research:
Ethanone, 1-(4-hydroxyphenyl)-, [1-(4-hydroxyphenyl)ethylidene]hydrazone, (E,E)is used as a research compound for its potential therapeutic properties. Its antioxidant and anti-inflammatory properties make it a promising candidate for the development of new drugs to treat various medical conditions.
Used in Drug Development:
Ethanone, 1-(4-hydroxyphenyl)-, [1-(4-hydroxyphenyl)ethylidene]hydrazone, (E,E)is used as a starting material or intermediate in the synthesis of new drugs. Its unique structure and properties can be leveraged to create novel therapeutic agents with improved efficacy and safety profiles.
Used in Antioxidant and Anti-inflammatory Applications:
Ethanone, 1-(4-hydroxyphenyl)-, [1-(4-hydroxyphenyl)ethylidene]hydrazone, (E,E)is used as an antioxidant and anti-inflammatory agent in the development of treatments for conditions associated with oxidative stress and inflammation, such as chronic diseases, autoimmune disorders, and age-related conditions.
Further research is needed to fully understand the potential applications of Ethanone, 1-(4-hydroxyphenyl)-, [1-(4-hydroxyphenyl)ethylidene]hydrazone, (E,E)- in the field of medicine and to explore its interactions with other molecules and biological systems.

Upstream product

• 99-93-4 4-Hydroxyacetophenone 

Downstream Products

• 99-93-4 4-Hydroxyacetophenone 
• 65124-88-1 1-(4-methoxyphenyl)ethanone <1-(4-methoxyphenyl)ethylidene>hydrazone 
• 85302-79-0 4,4'-diethoxy-α,α'-dimethylbenzalazine 

Relevant academic research and scientific papers

Rapid, chemoselective and facile synthesis of azines by hydrazine/I2

We report the reaction of hydrazine hydrate with carbonyl compounds in the presence of molecular iodine at 0-10°C, which affords symmetrical azines in excellent yields in 1 to 4 min without any adverse effect on other substituents. The reactions are rapid and chemoselective, afford excellent yields, and have high-purity products. The workup procedure is environmentally benign and does not require solvent extraction. Copyright Taylor & Francis Group, LLC.

Highly efficient practical procedure for the synthesis of azine derivatives under solvent-free conditions

A general and useful method for the synthesis of azines of aromatic aldehydes and ketones in good yields was elaborated. This reaction is carried out under solvent-free conditions and in the absence of catalyst to afford good yields of the relevant azines. The reaction is also environmentally friendly without the inconvenience of undesired by-products and has advantages over the previously reported methods. Products were characterized by the usual procedures (infrared, 1H NMR, and 13C NMR).

Selective protection of carbonyl compounds as azines and their facile regeneration

Carbonyl compounds with freshly prepared hydrazinium formate successfully yielded the corresponding azines in excellent yields. In turn, azines were deprotected to the corresponding carbonyls using triethylammonium chlorochromate chemoselectively. Copyright Taylor & Francis Group, LLC.

Cholesterol-based linear trimesogens: Synthesis and evaluation of mesomorphic behaviour

Several trimesogens consisting of benzalazine as a central mesogenic segment, connected linearly on both the terminals with the cholesteryl ester moieties through either even-even or odd-odd alkylene spacers, have been synthesised and investigated for the

SYNTHESIS AND MESOMORPHIC PROPERTIES OF THREE HOMOLOGOUS SERIES OF 4,4 prime -DIALKOXY- alpha , alpha prime -DIMETHYLBENZALAZINES.

Three homologous series of alpha , alpha prime -dimethylbenzalazines have been synthesized: 4,4 prime -dialkoxy- alpha , alpha prime -dimethylbenzalazines, 4,4 prime -dialkoxy-2,2 prime -dihydroxy- alpha , alpha prime -dimethylbenzalazines, and 4,4 prime -dialkoxy-2-hydroxy- alpha , alpha prime -dimethylbenzalazines. The influence of molecular structure on the mesomorphic properties was studied. Mesomorphic properties and phase transitions were determined using a polarizing hot-stage microscope and a differential scanning calorimeter. The introduction of one or two hydroxyl groups in position 2- or 2-and 2 prime -of the aromatic rings (4,4 prime -dialkoxy-2-hydroxy- alpha , alpha prime -dimethylbenzalazines and 4,4 prime -dialkoxy-2,2 prime -dihydroxy- alpha , alpha prime -dimethylbenzalazines respectively) gives molecules with an excellent mesogenic quality, and all the prepared compounds of these series exhibit mesomorphism. Compounds of the series with two hydroxyl groups exhibit smectic polymorphism which is not so in the case of the compounds of the other series. The melting temperatures are systematically lower for the 4,4 prime -dialkoxy-2-hydroxy- alpha , alpha prime -dimethylbenzalazines than for the other two series.