651302-41-9Relevant articles and documents
Facile synthesis of 5-hydroxy-l-lysine from d-galactose as a chiral-precursor
Guo, Lina,Liu, Taibao,Chen, Kai,Song, Tianbang,Wang, Peng George,Zhao, Wei
, p. 7310 - 7317 (2014)
A concise synthesis of (2S,5R) and (2S,5S)-5-hydroxy-lysine was achieved by utilizing d-galactose as a chiral-precursor with stereo retention. This synthetic strategy showcased the potential of utilizing carbohydrates as starting materials to prepare amino acids. Using the diazido intermediate, the derived β-d-galactopyranosyl and α-d-glucopyranosyl-(1→2)- β-d-galactosyl moieties were synthesized. This journal is the Partner Organisations 2014.
Synthesis of Unsaturated Aminopyranosides as Possible Transition State Mimics for Glycosidases
Jordan, Allan M.,Osborn, Helen M. I.,Stafford, Petra M.,Tzortzis, George,Rastall, Robert A.
, p. 705 - 717 (2007/10/03)
Four unsaturated aminopyranosides have been prepared as possible transition-state mimics targeted towards carbohydrate processing enzymes. The conformations of the protonated aminosugars have been investigated by molecular modelling and their ability to i