65132-43-6Relevant articles and documents
A-C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions
Hanson, Alicia M.,Perera, K. L. Iresha Sampathi,Kim, Jaekyoon,Pandey, Rajesh K.,Sweeney, Noreena,Lu, Xingyun,Imhoff, Andrea,Mackinnon, Alexander Craig,Wargolet, Adam J.,Van Hart, Rochelle M.,Frick, Karyn M.,Donaldson, William A.,Sem, Daniel S.
, p. 4720 - 4738 (2018/05/23)
Estrogen receptor-beta (ERβ) is a drug target for memory consolidation in postmenopausal women. Herein is reported a series of potent and selective ERβ agonists (SERBAs) with in vivo efficacy that are A-C estrogens, lacking the B and D estrogen rings. The
SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM
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Paragraph 0095; 00133-00134, (2015/06/08)
Disclosed are substituted (4'-hydroxylphenyl)cycloalkane compounds and there use as selective agonists of the estrogen receptor beta isoform (ΕΚβ). The disclosed compounds may be formulated as pharmaceutical compositions and administered to treat diseases
Organic reaction in water. Part 3: A facile method for reduction of aromatic rings using a Raney Ni-Al alloy in dilute aqueous alkaline solution under mild conditions
Tsukinoki, Takehito,Kanda, Tadashige,Liu, Guo-Bin,Tsuzuki, Hirohisa,Tashiro, Masashi
, p. 5865 - 5868 (2007/10/03)
Reduction of aromatic rings such as phenol, naphthalenes, biphenyls, acenaphthene, and acenaphthylene was smoothly performed using a Raney Ni-Al alloy in dilute aqueous alkaline solution without any organic solvents at 90°C under atmospheric pressure, and the corresponding reduced compounds were obtained in high yields. (C) 2000 Elsevier Science Ltd.